Etiology-Specific Mineralization Patterns in Patients with Labyrinthitis Ossificans

AJNR. American Journal of Neuroradiology
K BuchOsamu Sakai

Abstract

Our aim was to identify whether specific patterns of ossification in labyrinthitis ossificans are associated with the known risk factors. Labyrinthitis ossificans has been described as sequela of prior temporal bone trauma, prior infection, and other disorders including sickle cell disease. Specific patterns of mineralization in the membranous labyrinth associated with these risk factors has not been previously described. This was a retrospective study evaluating temporal bone CT scans at our institution from November 2005 to May 2018 in patients with labyrinthitis ossificans. Membranous labyrinthine structures evaluated for ossification included the following: basal, middle, and apical cochlear turns; lateral, posterior, and superior semicircular canals; and the vestibule for both ears in all patients. These structures were assigned a severity score, 0-4, based on degree of mineralization. Clinical records were reviewed for potential labyrinthitis ossificans risk factors. Basic descriptive statistics and a mixed model were used to correlate the degree and patterns of ossification with clinical history. Forty-four patients (58 ears) with labyrinthitis ossificans were identified and evaluated. The most common risk factors were c...Continue Reading

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Dec 14, 2019·AJNR. American Journal of Neuroradiology·J C BensonJ Lane

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