Etiopathogenesis of transient ischemic attacks and minor ischemic strokes: a community-based study in Segovia, Spain

Stroke; a Journal of Cerebral Circulation
A P SempereL E Clavería

Abstract

We sought to analyze the etiology and underlying vascular risk factors of transient ischemic attacks (TIAs) and minor ischemic strokes (MISs). We prospectively studied the vascular risk factors and etiologic categories in 235 patients with TIAs and MISs from a community-based register in a rural area of Spain. Five etiologic categories were considered: (1) cardioembolism, (2) large-artery atherosclerosis, (3) small-artery disease, (4) other etiologies, and (5) undetermined etiology. Systematic investigations included neuroimaging (CT/MRI) and vascular studies (duplex scan/MR angiography and angiography in selected cases). The two most frequent etiologic categories were small-artery disease (31%) and cardioembolism (26%). Large-artery atherosclerosis was detected in 11% of the patients. Significant carotid stenosis (> or =50%) was present in 13% of patients with carotid territory events. No cause could be found or it was uncertain in almost one third of the patients. The distribution of etiologic categories was similar in TIAs and MISs. The most prevalent vascular risk factors were as follows: arterial hypertension (50%), smoking (26%), atrial fibrillation (20%), hypercholesterolemia (17%), diabetes (15%), ischemic heart disease...Continue Reading

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Citations

May 21, 2005·Der Nervenarzt·C H NolteA Villringer
Aug 5, 2014·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Takeshi HayashiNorio Tanahashi
Jul 5, 2005·Expert Opinion on Investigational Drugs·M A KhanD P Mikhailidis
Dec 2, 2006·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Huey-Juan LinChia-Yu Chang
Sep 24, 2005·Clinical Radiology·E WidjajaUNKNOWN Sheffield Stroke Prevention Group
Oct 2, 2007·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·W D NiesenJ Noth

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