Eubacterium rangiferina, a novel usnic acid-resistant bacterium from the reindeer rumen.

Die Naturwissenschaften
Monica A SundsetKirsti E Praesteng

Abstract

Reindeer are able to eat and utilize lichens as an important source of energy and nutrients. In the current study, the activities of antibiotic secondary metabolites including usnic, antranoric, fumarprotocetraric, and lobaric acid commonly found in lichens were tested against a collection of 26 anaerobic rumen bacterial isolates from reindeer (Rangifer tarandus tarandus) using the agar diffusion method. The isolates were identified based on their 16S ribosomal ribonucleic acid (rRNA) gene sequences. Usnic acid had a potent antimicrobial effect against 25 of the isolates, belonging to Clostridiales, Enterococci, and Streptococci. Isolates of Clostridia and Streptococci were also susceptible to atranoric and lobaric acid. However, one isolate (R3_91_1) was found to be resistant to usnic, antranoric, fumarprotocetraric, and lobaric acid. R3_91_1 was also seen invading and adhering to lichen particles when grown in a liquid anaerobic culture as demonstrated by transmission electron microscopy. This was a Gram-negative, nonmotile rod (0.2-0.7 x 2.0-3.5 microm) with a deoxyribonucleic acid G + C content of 47.0 mol% and main cellular fatty acids including 15:0 anteiso-dimethyl acetal (DMA), 16:0 iso-fatty acid methyl ester (FAME), 1...Continue Reading

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Citations

Dec 25, 2009·Die Naturwissenschaften·Monica A SundsetSvein D Mathiesen
Jul 8, 2008·Microbial Ecology·Monica A SundsetAndré-Denis G Wright
Feb 27, 2010·Journal of Chemical Ecology·Line NybakkenVidar Selås
Nov 11, 2015·Microbiome·Irene Hanning, Sandra Diaz-Sanchez
Aug 26, 2009·FEMS Microbiology Ecology·Monica A SundsetAndré-Denis G Wright
Oct 13, 2016·Biological Reviews of the Cambridge Philosophical Society·Johan Asplund, David A Wardle
Mar 12, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Alice GadeaMaryvonne Charrier
Jul 1, 2017·Integrative and Comparative Biology·M Denise Dearing, Kevin D Kohl

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