Sep 12, 2019

Europium-Functionalized Flexible Luminescent Zeolite-like Supramolecular Assembly for Ratiometric Anthrax Biomarker Determination

ACS Applied Materials & Interfaces
Kai XingYulin Yang

Abstract

Anthrax spores have been a determining risk to human beings and animals across the world. As such, the qualitative monitoring toward dipicolinic acid (DPA), the unique biomarker of bacillus anthracis, is highly desired and being moved forward in health management. Herein, a breathing zeolite-like supramolecular assembly (ZSA), with the sra topology and 1D hexagon channel, is designed by controlling the bridging angle of the ditopic ligand after systematic analysis in topology. The solvent-dependent dynamic behavior is illustrated by powder X-ray diffraction and reflected in tunable luminescent emission based on solvent polarity parameters. According to the structural result and theoretical analysis, Eu3+ is anchored within the framework to form a ratiometric luminescent sensor successfully because of the abundant potential active site. After DPA addition, the resulting composite shows a sensitive and selective response in the linear range of 0-7.0 μM stemmed from absorbance energy-transfer emission and preferential coordination. The work we presented here may enrich the sensing platforms containing lanthanides and expand the potential application of ZSAs in clinical analysis.

  • References
  • Citations

References

  • We're still populating references for this paper, please check back later.
  • References
  • Citations

Citations

  • This paper may not have been cited yet.

Mentioned in this Paper

Biological Markers
Positron-Emission Tomography
Determination Aspects
UreG protein, Glycine max
Theoretical Study
Lanthanoid Series Elements
Site
X-Ray Diffraction
Angular
Spores, Fungal

Related Feeds

Anthrax Vaccines (ASM)

Three different types of anthrax vaccines are available; a live-attenuated, an alum-precipitated cell-free filtrate and a protein recombinant vaccine. The effectiveness between the three is uncertain, but the live-attenuated have shown to reduce the risk of anthrax with low adverse events. Here is the latest research on anthrax vaccines.

Anthrax

Anthrax toxin, comprising protective antigen, lethal factor, and oedema factor, is the major virulence factor of Bacillus anthracis, an agent that causes high mortality in humans and animals. Here is the latest research on Anthrax.

Anthrax Vaccines

Three different types of anthrax vaccines are available; a live-attenuated, an alum-precipitated cell-free filtrate and a protein recombinant vaccine. The effectiveness between the three is uncertain, but the live-attenuated have shown to reduce the risk of anthrax with low adverse events. Here is the latest research on anthrax vaccines.