Euthanasia

Current Protocols in Neuroscience
John Donovan, Patricia Brown

Abstract

Euthanasia of laboratory animals must be performed by trained personnel using appropriate techniques, equipment, and reagents in order to effect a death that is humane and satisfies research requirements. Acceptable methods of euthanasia are painless or minimize distress, and are quick and easy to perform, safe for those performing the procedure, and efficient and economic. They are aesthetically acceptable and are done in the absence of other animals. In addition, these methods do not result in gross histological or histochemical changes that would adversely affect research results. This unit offers protocols for euthanasia employing carbon dioxide asphyxiation (see Basic Protocol 1), pentobarbital overdose (see Basic Protocol 2), exsanguination, and cervical dislocation for the mouse, rat, hamster, and rabbit.

References

Mar 31, 2001·Journal of the American Veterinary Medical Association·UNKNOWN AVMA Panel on Euthanasia. American Veterinary Medical Association

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Citations

Jun 23, 2011·Journal of Visualized Experiments : JoVE·Reghann G LaFrance-Corey, Charles L Howe
Oct 12, 2013·Forensic Science, Medicine, and Pathology·Julia SautterLars Oesterhelweg
Jun 27, 2018·Current Protocols in Mouse Biology·Stephan C CollinsBinnaz Yalcin
Jun 20, 2019·Current Protocols in Neuroscience·Elisenda SanzG Stanley McKnight
Jul 2, 2015·Current Protocols in Neuroscience·Kalliopi IoannidouSusan C Barnett
Apr 2, 2015·Current Protocols in Neuroscience·Juan Carlos MarvizonBradley K Taylor
Jul 15, 2020·Current Protocols in Neuroscience·Sharon SunThomas Anthony Anderson
Mar 3, 2015·Current Protocols in Cell Biology·Isabelle DupinSandrine Etienne-Manneville
Feb 2, 2019·Current Protocols in Microbiology·Chris KayWendy Gibson
Jul 22, 2021·Current Protocols·Venkatraman RaviNagalingam Ravi Sundaresan

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