Evaluating analytical quality in clinical biochemistry laboratory using Six Sigma

Biochemia Medica
Xuehui MaoYong Wang

Abstract

In recent years, Six Sigma metrics has became the hotspot in all trades and professions, which contributes a general procedure to explain the performance on sigma scale. Nowadays, many large companies, such as General Healthcare, Siemens, etc., have applied Six Sigma to clinical medicine and achieved satisfactory results. In this paper, we aim to evaluate the process performance of our laboratory by using Sigma metrics, thereby choosing the correct analytical quality control approach for each parameter. This study was conducted in the clinical chemistry laboratory of Shandong Provincial Hospital. The five-months data of internal quality control were harvested for the parameters: amylase (AMY), lactate dehydrogenase (LD), potassium, total bilirubin (TBIL), triglyceride, aspartate aminotransferase (AST), uric acid, high density lipoprotein-cholesterol (HDL-C), alanine aminotransferase (ALT), urea, sodium, chlorine, magnesium, alkaline phosphatase (ALP), creatinine (CRE), total protein, creatine kinase (CK), total cholesterol, glucose (GLU), albumin (ALB). Sigma metrics were calculated using total allowable error, precision and percent bias for the above-mentioned parameters. Sigma values of urea and sodium were below 3. Sigma val...Continue Reading

References

Apr 3, 2012·Indian Journal of Clinical Biochemistry : IJCB·Bhawna SinghVenkatesan Mallika
Mar 13, 2014·Clinical Chemistry and Laboratory Medicine : CCLM·Koen HensSten Westgard

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Citations

Nov 28, 2019·Journal of Clinical Laboratory Analysis·Bingfei ZhouYoude Cao
Jul 20, 2018·Biochemia Medica·Sten WestgardJames O Westgard
Dec 15, 2020·Journal of Clinical Laboratory Analysis·Yong XiaLing Ji
Jul 19, 2021·International Journal of Laboratory Hematology·Wafaa Ahmed El-NeanaeyReham Abdel Haleem Abo Elwafa

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