Evaluating competing and emerging technologies for stereotactic body radiotherapy and other advanced radiotherapy techniques

Clinical Oncology : a Journal of the Royal College of Radiologists
A G R MartinN G Burnet

Abstract

Stereotactic body radiotherapy (SBRT) refers to the precise irradiation of an image-defined extracranial lesion, using a high total radiation dose delivered in a small number of fractions. A significant proportion of SBRT treatment has been successfully delivered using conventional gantry-based linear accelerators with appropriate image guidance and motion management techniques, although a number of specialist systems are also available. Evaluating the competing SBRT technologies is difficult due to frequent refinements to all major platforms. Comparison of geometric accuracy or treatment planning performance can be hard to interpret and may not provide much useful information. Nevertheless, a general specification overview can provide information that may help radiotherapy providers decide on an appropriate system for their centre. A number of UK randomised controlled trials (RCTs) have shown that better radiotherapy techniques yield better results. RCTs should play an important part in the future evaluation of SBRT, especially where there is a smaller volume of existing data, and where outcomes from conventional radiotherapy are very good. RCT comparison of SBRT with surgery is more difficult due to the radically different tr...Continue Reading

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Citations

Jan 23, 2016·Clinical Oncology : a Journal of the Royal College of Radiologists·F Macbeth, T Treasure
Jun 3, 2016·Clinical Oncology : a Journal of the Royal College of Radiologists·S Hargreaves, C Comins
Oct 1, 2016·Clinical Oncology : a Journal of the Royal College of Radiologists·R Jena
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Oct 28, 2019·Journal of Medical Imaging and Radiation Oncology·Stephen ChinAnanya Choudhury
Nov 20, 2020·International Journal of Molecular Sciences·Kalaiyarasi RagunathanValentyn Oksenych
Nov 13, 2020·BJR Open·Patricia SansourekidouWen-Hung Kuo

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