Evaluating movement of patients with Carbapenem-Resistant Enterobacteriaceae infections in the Greater Atlanta Metropolitan Area using social network analysis

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Chris W BowerScott K Fridkin

Abstract

Carbapenem-resistant Enterobacteriaceae (CRE) are an urgent threat with potential for rapid spread. We evaluated the role of Medicare patient movement between facilities to model the spread of CRE within a region. Through population-based CRE surveillance in the 8-county Atlanta Metropolitan area (population 4.1 million), all Escherichiacoli, Enterobacter spp, or Klebsiella spp. resistant to ≥1 carbapenem collected from urine or a normally sterile site were reported from residents. CRE was attributed to a facility based on timing of culture and facility exposures in the previous year; centrality metrics were calculated from 2016 Medicare data and compared to CRE-transfer derived centrality metrics by Spearman correlation. During 2016, 283 incident CRE cases with concurrent or prior year facility stays were identified; cases were attributed mostly to acute care hospitals (ACH: 141, 50%) and skilled nursing facilities (SNF: 113, 40%), and less frequently to long term acute care hospitals (LTACH: 29, 10%). Attribution was widespread, originating at 17 of 20 ACH (85%), 7 of 8 (88%) LTACH, but only 35 of 65 (54%) SNFs. Betweenness of Medicare patient-transfers strongly correlated with betweenness of CRE case-transfer data in ACHs (r...Continue Reading

References

Feb 19, 2011·American Journal of Public Health·Bruce Y LeeSusan S Huang
Apr 5, 2011·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Maia LesoskyJanet Raboud
Jun 10, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Neil GuptaAlexander J Kallen
Aug 26, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Sarah Y WonUNKNOWN Centers for Disease Control and Prevention Epicenter Program
Oct 15, 2013·Current Infectious Disease Reports·Eva-Brigitta KruseHilmar Wisplinghoff
Jan 29, 2014·Proceedings of the National Academy of Sciences of the United States of America·Mariano CiccoliniMark E J Woolhouse
Sep 16, 2014·Analytical Chemistry·Kamonnaree ChotinantakulAlbert Schulte
Oct 8, 2014·JAMA : the Journal of the American Medical Association·Lauren EpsteinAlexander J Kallen
Jun 16, 2015·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Jacob E SimmeringPhilip M Polgreen
Aug 21, 2015·Emerging Infectious Diseases·Scott K FridkinRuth Lynfield
Aug 4, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Michael J RayWilliam E Trick
May 5, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Damon J A TothMatthew H Samore
Feb 8, 2018·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Michael J RayWilliam E Trick
Apr 6, 2018·MMWR. Morbidity and Mortality Weekly Report·Kate Russell WoodworthDenise M Cardo

❮ Previous
Next ❯

Citations

May 11, 2021·Frontiers in Cellular and Infection Microbiology·Hsin-Yu ChenPo-Ren Hsueh
May 28, 2021·Current Opinion in Infectious Diseases·Anna StachelUNKNOWN CDC MInD Healthcare Program

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carbapenems (ASM)

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

Carbapenems

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

Related Papers

JAMA : the Journal of the American Medical Association
Mitchell J Schwaber, Yehuda Carmeli
Journal of the American Medical Directors Association
Paula LesterDing-Geng Chen
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Damon J A TothMatthew H Samore
Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
J C ThomasG Hancock
© 2022 Meta ULC. All rights reserved