Evaluating the clinical usefulness of structured questions in parosmia assessment

The Laryngoscope
Basile N LandisThomas Hummel

Abstract

Parosmia and phantosmia relate to distorted odor perceptions. Little is known about their clinical significance. Measuring phantosmia and parosmia is still not possible. Today, assessment of parosmia or phantosmia relies mainly upon the patient's interview and the physician's experience. Therefore, we investigated the clinical usefulness of four structured questions in comparison to the patient's history regarding their accuracy in terms of the presence of odor distortions. Tertiary care center outpatient clinic analyses. Responses from 193 patients were analyzed. All patients underwent full olfactory work-up (ear, nose, and throat examination, Sniffin' Sticks testing, structural brain imaging) and filled in a questionnaire with four parosmia questions and six questions regarding characteristics and severity of the parosmia. These responses formed the bases of a numerical parosmia score. Patients with parosmia showed significantly lower parosmia scores (P <.001) when compared to either patients with phantosmia or patients without odor distortions. Two questions could be identified that showed a high association to the presence or absence of parosmia. The present results confirm reports on the high frequency of parosmia and phan...Continue Reading

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Citations

Jul 26, 2013·Psychological Medicine·I CroyT Hummel
Oct 15, 2013·Chemical Senses·Donald A Leopold, David E Hornung
Jan 5, 2016·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·DaHai YangXin Wang
Dec 15, 2015·Clinical Neurology and Neurosurgery·J FrasnelliE de Guise
May 25, 2012·Acta Oto-laryngologica·Seok-Chan HongThomas Hummel
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Nov 20, 2020·The Laryngoscope·David T LiuThomas Hummel
Aug 21, 2020·Neuroscience and Biobehavioral Reviews·Sarah Ellen CarnemollaAurélie L Manuel
Oct 24, 2020·Scientific Reports·David T LiuBertold Renner
Mar 4, 2021·PloS One·Julian J WeissUNKNOWN Yale IMPACT Research Team
Apr 7, 2021·Laryngoscope Investigative Otolaryngology·José G GurrolaSteven W Cheung
Jun 27, 2019·ORL; Journal for Oto-rhino-laryngology and Its Related Specialties·Emilia IannilliThomas Hummel

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