Evaluating the effectiveness of a self-management exercise intervention on wound healing, functional ability and health-related quality of life outcomes in adults with venous leg ulcers: a randomised controlled trial.

International Wound Journal
Jane A O'BrienHelen Edwards

Abstract

Exercise that targets ankle joint mobility may lead to improvement in calf muscle pump function and subsequent healing. The objectives of this research were to assess the impact of an exercise intervention in addition to routine evidence-based care on the healing rates, functional ability and health-related quality of life for adults with venous leg ulcers (VLUs). This study included 63 patients with VLUs. Patients were randomised to receive either a 12-week exercise intervention with a telephone coaching component or usual care plus telephone calls at the same timepoints. The primary outcome evaluated the effectiveness of the intervention in relation to wound healing. The secondary outcomes evaluated physical activity, functional ability and health-related quality of life measures between groups at the end of the 12 weeks. A per protocol analysis complemented the effectiveness (intention-to-treat) analysis to highlight the importance of adherence to an exercise intervention. Intention-to-treat analyses for the primary outcome showed 77% of those in the intervention group healed by 12 weeks compared to 53% of those in the usual care group. Although this difference was not statistically significant due to a smaller than expected...Continue Reading

References

Nov 1, 1995·Journal of Vascular Surgery·T L BackR W Hobson
May 1, 1993·Medicine and Science in Sports and Exercise·L DipietroE R Nadel
Apr 14, 1999·The British Journal of Surgery·D YangM C Stacey
Nov 28, 2001·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·N A StottsJ Maklebust
Jan 14, 2004·Journal of Vascular Surgery·Frank T PadbergSue Ann Sisto
Mar 5, 2004·The British Journal of Dermatology·D J MargolisW Bilker
Mar 11, 2004·Journal of Clinical Nursing·Anke PersoonTheo van Achterberg
Oct 27, 2004·Lancet·Stanton NewmanKathleen Mulligan
Apr 30, 2005·Clinical Rehabilitation·C J T van UdenH Wollersheim
Jun 9, 2005·International Journal of Dermatology·Luciana P Fernandes Abbade, Sidnei Lastória
Jul 13, 2005·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·T QiaoF Ran
Jul 11, 2006·International Journal of Nursing Studies·Maud M HeinenTheo van Achterberg
Aug 9, 2007·Physical Therapy·Deb A KegelmeyerSandra K Kostyk
Oct 17, 2007·Archives of Dermatology·Maud M HeinenTheo van Achterberg
Feb 23, 2008·Journal of Applied Physiology·Katherine A RadekCharles E Wade
Aug 8, 2009·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Shanu K KurdDavid J Margolis
Sep 20, 2012·Journal of Wound Care·H MeagherP A Grace
Jan 15, 2014·Journal of Wound, Ostomy, and Continence Nursing : Official Publication of the Wound, Ostomy and Continence Nurses Society·Teresa J KelechiGreg Loftis
Jul 22, 2014·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Elizabeth YimRobert S Kirsner

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Citations

Jun 8, 2018·International Wound Journal·Markos KlonizakisGarry A Tew
Jul 18, 2018·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Andrew JullJill Waters
Apr 27, 2019·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Victoria TeamCarolina D Weller
Jun 13, 2019·Revista gaúcha de enfermagem·Marcelo Henrique da SilvaMiriam Aparecida Barbosa Merighi
Mar 10, 2020·Journal of Wound, Ostomy, and Continence Nursing : Official Publication of the Wound, Ostomy and Continence Nurses Society·Teresa J KelechiMartina Mueller
Sep 15, 2020·The International Journal of Lower Extremity Wounds·Thomas Vedste AagaardStig Brorson
Mar 12, 2021·Cardiology and Therapy·Vwaire OrhurhuDua Anahita
Nov 19, 2021·The International Journal of Lower Extremity Wounds·Sothida NantakoolKittipan Rerkasem

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