Evaluating the effectiveness of fish consumption advisories: modeling prenatal, postnatal, and childhood exposures to persistent organic pollutants

Environmental Health Perspectives
Matthew J BinningtonFrank Wania

Abstract

Because human exposure to persistent organic pollutants (POPs) occurs mainly through ingestion of contaminated food, regulatory bodies issue dietary consumption advisories to describe safe intake levels for food items of concern, particularly fish. Our study goal was to estimate the effectiveness of fish consumption advisories in reducing exposure of infants and children to POPs. We used the time-variant mechanistic model CoZMoMAN to estimate and compare prenatal, postnatal, and childhood exposure to polychlorinated biphenyl congener PCB-153 under different scenarios of maternal guideline adherence for both hypothetical constant and realistic time-variant chemical emissions. The scenarios differed in terms of length of compliance (1 vs. 5 years), extent of fish substitution (all vs. half), and replacement diet (uncontaminated produce vs. beef). We also estimated potential exposure reductions for a range of theoretical chemicals to explore how guideline effectiveness varies with a chemical's partitioning and degradation properties. When assuming realistic time periods of advisory compliance, our findings suggest that temporarily eliminating or reducing maternal fish consumption is largely ineffective in reducing pre- and postnat...Continue Reading

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Citations

Feb 4, 2014·Environmental Health Perspectives·Kellyn S Betts
Jul 4, 2017·Scandinavian Journal of Public Health·Anne Seneca TerkelsenEva Cecilie Bonefeld-Jørgensen
Dec 16, 2016·International Journal of Circumpolar Health·Eva-Maria Krümmel, Andrew Gilman
Dec 16, 2016·International Journal of Circumpolar Health·Khaled AbassArja Rautio
Oct 23, 2015·Environmental Science and Pollution Research International·Su Hyun ParkHyesook Park
Nov 28, 2018·Environmental Research·Ryan S D CalderElsie M Sunderland

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Software Mentioned

CoZMoMAN
Human
ACC
CoZMoPOP2

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