Evaluating the effectiveness of selected community-level interventions on key maternal, child health, and prevention of mother-to-child transmission of HIV outcomes in three countries (the ACCLAIM Project): a study protocol for a randomized controlled trial

Trials
Godfrey B WoelkProject ACCLAIM Study Group

Abstract

Efforts to scale up and improve programs for prevention of mother-to-child transmission of HIV (PMTCT) have focused primarily at the health facility level, and limited attention has been paid to defining an effective set of community interventions to improve demand and uptake of services and retention. Many barriers to PMTCT are also barriers to pregnancy, childbirth, and postnatal care faced by mothers regardless of HIV status. Demand for maternal and child health (MCH) and PMTCT services can be limited by critical social, cultural, and structural barriers. Yet, rigorous evaluation has shown limited evidence of effectiveness of multilevel community-wide interventions aimed at improving MCH and HIV outcomes for pregnant women living with HIV. We propose to assess the effect of a package of multilevel community interventions: a social learning and action component, community dialogues, and peer-led discussion groups, on the demand for, uptake of, and retention of HIV positive pregnant/postpartum women in MCH/PMTCT services. This study will undertake a three-arm randomized trial in Swaziland, Uganda, and Zimbabwe. Districts/regions (n = 9) with 45 PMTCT-implementing health facilities and their catchment areas (populations 7,300-2...Continue Reading

Associated Clinical Trials

References

Jan 1, 1988·Health Education Quarterly·K R McLeroyK Glanz
Aug 21, 2001·International Journal of Epidemiology·N Krieger
Aug 13, 2005·Social Science & Medicine·Mary J De SilvaSharon R Huttly
Jul 30, 2009·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Dean PeacockThomas J Coates
Mar 25, 2010·BMJ : British Medical Journal·Kenneth F SchulzUNKNOWN CONSORT Group
Sep 7, 2012·BMJ : British Medical Journal·Marion K CampbellUNKNOWN CONSORT Group
Oct 19, 2012·The Cochrane Database of Systematic Reviews·Serena BrusamentoJosip Car
Feb 20, 2013·Evaluation Review·Diana Epstein, Jacob Alex Klerman
Mar 22, 2013·AIDS Education and Prevention : Official Publication of the International Society for AIDS Education·William J UgarteBirgitta Essén
Jul 10, 2014·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Carol UnderwoodElizabeth C Mallalieu

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Citations

Aug 24, 2017·Lab on a Chip·Catherine E MajorsRebecca Richards-Kortum
Jul 19, 2017·International Breastfeeding Journal·Helen M NabweraMartha K Mwangome
Aug 4, 2021·African Journal of Primary Health Care & Family Medicine·Mercy PindaniGenesis Chorwe-Sungani

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Methods Mentioned

BETA
circumcision

Software Mentioned

STATA
GLASER
Info
Epi
SASCAT
SPSS
ACCLAIM
SAS
SCAT

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