Evaluating the Efficacy of Different Platelet-Rich Plasma Regimens for Management of Androgenetic Alopecia: A Single-Center, Blinded, Randomized Clinical Trial

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]
Amelia K Hausauer, Derek H Jones

Abstract

Studies suggest platelet-rich plasma (PRP) may mitigate androgenetic alopecia (AGA), but each varies in the frequency of and interval between treatments. To compare the efficacy, satisfaction, tolerability, and safety of 2 initial PRP injection protocols over 6 months. Prospective, randomized, single-blinded trial among 40 patients with moderate AGA. Participants received subdermal PRP injections according to 1 of 2 treatment protocols: 3 monthly sessions with booster 3 months later (Group 1) or 2 sessions every 3 months (Group 2). Folliscope hair count and shaft caliber, global photography, and patient satisfaction questionnaires were obtained at baseline, 3 months, and 6 months. At 6 months, both groups demonstrated statistically significant increases in hair count (p < .001). These improvements occurred more rapidly and more profoundly for Group 1 (mean percent change: Group 1, 29.6 ± 13.6 vs Group 2, 7.2 ± 10.4; p < .001). Shaft caliber also increased significantly with no difference between groups. Treatments produced high satisfaction (82% "satisfied" or "highly satisfied") and were safe and well tolerated (mean pain score 2.1). Subdermal PRP injections are an efficacious and tolerable therapy among men and women with AGA...Continue Reading

References

Jun 1, 1992·Journal of the American Academy of Dermatology·T F Cash
Sep 25, 1998·BMJ : British Medical Journal·R Sinclair
Oct 20, 1998·Journal of the American Academy of Dermatology·K D KaufmanG J Gormley
May 18, 1999·Dermatologic Clinics·R M Bernstein, W R Rassman
Apr 20, 2000·The Journal of Investigative Dermatology·L MecklenburgR Paus
Mar 5, 2004·The British Journal of Dermatology·A G Messenger, J Rundegren
Oct 20, 2006·Plastic and Reconstructive Surgery·Carlos Oscar UebelPedro Martins
Apr 3, 2007·Journal of Periodontology·Hesham El-SharkawyThomas E Van Dyke
Apr 15, 2009·Expert Opinion on Pharmacotherapy·Antonella Tosti, Bruna Duque-Estrada
Oct 5, 2010·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Jeong Mok ChoSang Woo Lee
Oct 20, 2010·Archives of Dermatology·José Manuel MellaGordon Guyatt
Sep 3, 2011·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Megumi TakikawaTomoharu Kiyosawa
Mar 30, 2012·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Zheng Jun LiYoung Lee
Jan 3, 2013·Journal of the European Academy of Dermatology and Venereology : JEADV·J-S KangS B Cho
Apr 22, 2014·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Satoshi KushidaKenji Kusumoto
Aug 12, 2014·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Giovanni SchiavoneDamiano Abeni
Feb 28, 2015·Journal of Cutaneous and Aesthetic Surgery·Maria-Angeliki GkiniKonstantinos Kouskoukis
Jul 17, 2015·International Journal of Trichology·Gkini Maria-AngelikiKouskoukis Konstantinos
Sep 25, 2015·Stem Cells Translational Medicine·Pietro GentileValerio Cervelli
Apr 2, 2016·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Rubina Alves, Ramon Grimalt
Oct 28, 2016·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Carlos J PuigMichelle Peters
Sep 16, 2016·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Aditya K Gupta, Jessie Carviel

❮ Previous
Next ❯

Citations

Apr 24, 2019·Journal of Cosmetic Dermatology·Jusleen Ahluwalia, Sabrina G Fabi
Nov 13, 2019·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Amelia K Hausauer, Shannon Humphrey
Nov 27, 2019·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Amelia K Hausauer, Shannon Humphrey
Feb 23, 2020·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Jeanette M Black
Mar 19, 2019·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Aditya K GuptaCarlos J Puig
Apr 6, 2020·The British Journal of Dermatology·M L W JuhaszJ Shapiro
May 16, 2020·The Journal of Dermatological Treatment·Adam G EvansSalam Kassis
May 22, 2019·Aesthetic Surgery Journal·Nina Semsarzadeh, Shilpi Khetarpal
Dec 12, 2019·Revista latino-americana de enfermagem·Andrea Pinto Leite Ribeiro, Beatriz Guitton Renaud Baptista de Oliveira
Jun 23, 2019·Clinical Drug Investigation·Qian QuZhiqi Hu
Aug 8, 2020·Dermatologic Therapy·Aditya K GuptaMary Bamimore
Jan 13, 2021·Journal of the American Academy of Dermatology·Meyeneobong InyangRonda S Farah
Jul 11, 2020·Journal of the American Academy of Dermatology·Danielle P DubinHooman Khorasani
Jun 1, 2021·Dermatologic Clinics·Christina N LawsonValerie D Callender
Jun 1, 2021·Dermatologic Clinics·Aditya K GuptaJeffrey A Rapaport

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved