Evaluating the lateral resolution of the adaptive optics scanning laser ophthalmoscope

Journal of Biomedical Optics
Yuhua Zhang, Austin Roorda

Abstract

We present a statistical assessment of the lateral resolution of the adaptive optics scanning laser ophthalmoscope (AOSLO). We adopt a 2-D Gaussian function to approximate the AOSLO point spread function (PSF), which is dominated by the residual wavefront aberration and characterized by the Strehl ratio. Thus, we derive the lateral resolution in the presence of residual wave aberrations, which is inversely proportional to square root of the Strehl ratio. The modeling, while not sufficient in describing the fine structure of the real PSF, demonstrates good conformance to the lateral cross section of the real PSF. With this model, the lateral resolution of our current AOSLO was computed to be 1.65 to 2.33 microm, which agreed well with the actual result. We also reveal the relationships among the lateral resolution and other three measures of the AOSLO imaging property including the Strehl ratio, the PSF, and the root mean square (rms) of wavefront aberration.

References

Nov 14, 1997·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·J LiangD T Miller
Aug 8, 2001·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·J PorterD R Williams
Nov 19, 2003·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·William J Donnelly, Austin Roorda
Jan 13, 2004·Journal of Biomedical Optics·Krishnakumar VenkateswaranFernando Romero-Borja
May 6, 2002·Optics Express·Austin RoordaMelanie Campbell
Apr 15, 1987·Applied Optics·R H WebbF C Delori
Mar 15, 1989·Applied Optics·F C Delori, K P Pflibsen

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Citations

Apr 23, 2013·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Sung Pyo ParkStanley Chang
Feb 28, 2013·European Journal of Human Genetics : EJHG·Sung Pyo ParkStanley Chang
Oct 13, 2006·Nature Reviews. Neuroscience·Amir Rattner, Jeremy Nathans
Nov 9, 2010·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Pooja GodaraJoseph Carroll
Sep 30, 2010·PloS One·Peter Charbel IssaHendrik P N Scholl
Sep 13, 2014·Ophthalmic Surgery, Lasers & Imaging Retina·Sung Pyo ParkStephen H Tsang
Dec 30, 2014·IEEE Journal of Selected Topics in Quantum Electronics : a Publication of the IEEE Lasers and Electro-optics Society·Robert J ZawadzkiJohn S Werner
May 23, 2008·Progress in Retinal and Eye Research·Adrian Gh Podoleanu, Richard B Rosen
Aug 19, 2008·Experimental Eye Research·Joy A Martin, Austin Roorda
Sep 23, 2016·Journal of Biomedical Optics·Peng XiaoAlbert Claude Boccara
Jun 13, 2019·Seminars in Ophthalmology·Omar AbdelAlJennifer K Sun
Feb 9, 2012·Cornea·Yee Onn KokSeng Chee Loon
Dec 11, 2006·Optics Express·Kate GrieveAustin Roorda
Sep 25, 2019·Indian Journal of Ophthalmology·Ruchir A MehtaNaresh K Yadav
Jun 24, 2011·Biomedical Optics Express·Brian Vohnsen, Diego Rativa
Jul 1, 2017·Biomedical Optics Express·Michael Pircher, Robert J Zawadzki
Jun 2, 2018·International Journal of Endocrinology·Sonja G KarstJennifer K Sun
Apr 13, 2007·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Yuhua Zhang, Austin Roorda
Aug 16, 2016·Optics Letters·Jing LuYuhua Zhang
Mar 30, 2013·Retina·Judy E Kim, Mina Chung

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