Evaluating the levels of salivary alkaline and acid phosphatase activities as biochemical markers for periodontal disease: A case series.

Dental Research Journal
Sarita Dabra, Preetinder Singh

Abstract

The purpose of this study was to determine the salivary levels of alkaline phosphatase (ALP) and acid phosphatase (ACP) activities in patients with periodontal disease and to evaluate the use of these enzymes as biochemical markers for periodontal tissue damage. In this prospective analytical study, we examined the activities of salivary ALP and ACP in patients with periodontal disease, before and after periodontal treatment. The experimental groups consisted of 20 gingivitis patients and 20 periodontitis patients and the control group had healthy subjects (20 samples). The stimulated saliva of the patient was collected in a sterile test tube and analyzed using Hitachi's Diagnostic Automatic Analyser. Periodontal disease was determined based on clinical parameters such as gingival index, probing depth and clinical attachment loss. Patients with periodontal disease were under conventional periodontal treatment. The statistical analysis applied was Student's t-test. Probabilities less than 0.05 (P < 0.05) were considered significant. The obtained results showed statistically significant increased activities of ALP and ACP in saliva from patients with periodontal disease in relation to control group. A significant reduction in the...Continue Reading

Citations

Sep 21, 2013·Biomarkers in Medicine·Eran FrontRafael M Nagler
Sep 22, 2015·Frontiers in Cellular and Infection Microbiology·Suk Ji, Youngnim Choi
Aug 17, 2018·Current Stem Cell Research & Therapy·Young-Dan ChoYang-Jo Seol
Oct 6, 2018·Infectious Disorders Drug Targets·Fatemeh Ahmadi-MotamayelJalal Poorolajal
Apr 23, 2020·Journal of Family Medicine and Primary Care·Abhilasha S PatilShantanu B Pharande
Apr 4, 2021·Diagnostics·Liza L RamenzoniPatrick R Schmidlin

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