Evaluating the Prediction of Brain Maturity From Functional Connectivity After Motion Artifact Denoising

Cerebral Cortex
Ashley N NielsenBradley L Schlaggar

Abstract

The ability to make individual-level predictions from neuroanatomy has the potential to be particularly useful in child development. Previously, resting-state functional connectivity (RSFC) MRI has been used to successfully predict maturity and diagnosis of typically and atypically developing individuals. Unfortunately, submillimeter head motion in the scanner produces systematic, distance-dependent differences in RSFC and may contaminate, and potentially facilitate, these predictions. Here, we evaluated individual age prediction with RSFC after stringent motion denoising. Using multivariate machine learning, we found that 57% of the variance in individual RSFC after motion artifact denoising was explained by age, while 4% was explained by residual effects of head motion. When RSFC data were not adequately denoised, 50% of the variance was explained by motion. Reducing motion-related artifact also revealed that prediction did not depend upon characteristics of functional connections previously hypothesized to mediate development (e.g., connection distance). Instead, successful age prediction relied upon sampling functional connections across multiple functional systems with strong, reliable RSFC within an individual. Our result...Continue Reading

References

Oct 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·B BiswalJ S Hyde
May 8, 2004·Methods in Enzymology·Kevin J BlackJoel S Perlmutter
May 19, 2004·Proceedings of the National Academy of Sciences of the United States of America·Nitin GogtayPaul M Thompson
Apr 16, 2005·Current Opinion in Neurobiology·B J CaseyTodd A Hare
Jun 25, 2005·Proceedings of the National Academy of Sciences of the United States of America·Michael D FoxMarcus E Raichle
Aug 8, 2007·Proceedings of the National Academy of Sciences of the United States of America·Damien A FairBradley L Schlaggar
Aug 21, 2007·Nature Reviews. Neuroscience·Michael D Fox, Marcus E Raichle
Feb 12, 2008·Trends in Cognitive Sciences·Nico U F DosenbachSteven E Petersen
Apr 3, 2009·Journal of Neurophysiology·Michael D FoxMarcus E Raichle
May 5, 2009·PLoS Computational Biology·Damien A FairSteven E Petersen
Jul 22, 2009·PLoS Biology·Kaustubh SupekarVinod Menon
Oct 28, 2009·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R Cameron CraddockHelen S Mayberg
Mar 12, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Gordon L ShulmanMaurizio Corbetta
Sep 11, 2010·Science·Nico U F DosenbachBradley L Schlaggar
Jun 10, 2011·Journal of Neurophysiology·B T Thomas YeoRandy L Buckner
Aug 4, 2011·NeuroImage·Koene R A Van DijkRandy L Buckner
Oct 20, 2011·NeuroImage·Danielle S BassettKelvin O Lim
Nov 22, 2011·Neuron·Jonathan D PowerSteven E Petersen
Jun 8, 2012·Frontiers in Human Neuroscience·Wei DuTülay Adali
Aug 21, 2012·Current Biology : CB·Timothy T BrownAnders M Dale
May 1, 2013·Frontiers in Computational Neuroscience·Svyatoslav VergunVivek Prabhakaran
Sep 3, 2013·NeuroImage·Jonathan D PowerSteven E Petersen
Sep 14, 2013·AJNR. American Journal of Neuroradiology·B SundermannB Pfleiderer
Oct 5, 2013·Frontiers in Human Neuroscience·Jared A NielsenJeffrey S Anderson
Nov 26, 2013·NeuroImage·Anastasia YendikiBruce Fischl
Jan 15, 2014·Cerebral Cortex·Guray ErusRuben C Gur
Mar 4, 2014·Human Brain Mapping·Emiliano SantarnecchiSimone Rossi
Apr 25, 2014·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Deanna J GreeneBradley L Schlaggar
Mar 4, 2015·NeuroImage·Budhachandra S KhundrakpamUNKNOWN Brain Development Cooperative Group

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Citations

Jun 4, 2019·The Review of Scientific Instruments·Muriah D WheelockAdam T Eggebrecht
Sep 2, 2020·Annals of Neurology·Melanie E FieldsJin-Moo Lee
Nov 3, 2020·Journal of Cognitive Neuroscience·Peter R MillarDavid A Balota
Nov 13, 2020·Developmental Cognitive Neuroscience·Kristina M RapuanoB J Casey
Feb 6, 2021·Translational Psychiatry·Feliberto de la CruzKarl-Jürgen Bär
Oct 24, 2020·APL Bioengineering·Alice SegatoElena De Momi
Feb 23, 2020·Neuron·Zaixu CuiTheodore D Satterthwaite
Jan 27, 2020·Biological Psychiatry : Cognitive Neuroscience and Neuroimaging·Ashley N NielsenDeanna J Greene
Aug 25, 2020·NeuroImage·Ann-Marie G de LangeKlaus P Ebmeier
Jun 13, 2021·NeuroImage·Emily S Finn, Monica D Rosenberg
Aug 12, 2020·Neuron·Dillan J NewboldNico U F Dosenbach
Aug 15, 2021·NeuroImage·Jiahe ZhangSusan Whitfield-Gabrieli

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