Evaluating the relationships of hypoglycaemia and HbA1c with screening-detected diabetes distress in type 1 diabetes

Endocrinology, Diabetes & Metabolism
Peter J ToddPratik Choudhary

Abstract

To explore the relationship between diabetes distress, glucose control and awareness of hypoglycaemia in adults with type 1 diabetes. We performed a cross-sectional study using data collected from 280 consecutive type 1 diabetes patients who used a routine clinic consultation tool that recorded HbA1c, hypoglycaemia awareness (measured using the Gold score) and diabetes distress (measured using the Diabetes Distress Scale 2 [DDS2]). We assessed correlations between DDS2 and HbA1c and DDS2 and Gold score and performed an ordinal regression analysis to identify factors contributing to distress. Diabetes distress was significantly correlated with HbA1c (r = .319, P < .001) and Gold score (r = .258, P < .001) independently and with synergistic effect. Female gender was also associated with diabetes distress, while age, BMI, duration of diabetes, severity of complications and use of CSII pumps were not. Occurrence of severe hypoglycaemia (SH) episodes increased with Gold score in a linear manner throughout the scale. This study has identified new evidence of a significant, independent relationship between diabetes distress measured by the DDS2 and reduced awareness of hypoglycaemia in people with type 1 diabetes. It also demonstrates...Continue Reading

References

Jun 1, 1995·Diabetes Care·W H PolonskyC E Schwartz
Mar 1, 2005·Diabetes Care·William H PolonskyRichard A Jackson
May 14, 2008·Annals of Family Medicine·Lawrence FisherWilliam H Polonsky
Jun 23, 2009·Diabetic Medicine : a Journal of the British Diabetic Association·L FisherD Hessler
Sep 15, 2011·Diabetic Medicine : a Journal of the British Diabetic Association·H A RogersS A Amiel
May 25, 2013·Diabetic Medicine : a Journal of the British Diabetic Association·L E JoensenI Willaing
May 29, 2013·Diabetic Medicine : a Journal of the British Diabetic Association·A NicolucciUNKNOWN DAWN2 Study Group
Jun 6, 2013·Diabetes Care·Lawrence FisherLisa A Strycker
Mar 15, 2015·Journal of Diabetes and Its Complications·Lawrence FisherVicky Bowyer
Apr 14, 2015·Diabetic Medicine : a Journal of the British Diabetic Association·R B StrandbergB Rokne
Sep 29, 2015·Current Diabetes Reports·Jackie SturtKate McCarthy
Oct 18, 2016·Diabetic Medicine : a Journal of the British Diabetic Association·L FisherL A Strycker
Dec 19, 2015·Diabetes Care·Ruth S WeinstockUNKNOWN T1D Exchange Severe Hypoglycemia in Older Adults With Type 1 Diabetes Study Group
Apr 28, 2016·Journal of Diabetes and Its Complications·Lawrence FisherAnne Peters
May 13, 2017·Diabetic Medicine : a Journal of the British Diabetic Association·D M HesslerV Bowyer

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Citations

Oct 14, 2018·Diabetic Medicine : a Journal of the British Diabetic Association·L JoensenI Willaing
Jun 10, 2019·Diabetic Medicine : a Journal of the British Diabetic Association·T A F WylieR I G Holt
Aug 14, 2018·Journal of Diabetes Science and Technology·Aneesah Khan, Pratik Choudhary
Mar 8, 2021·Translational Behavioral Medicine·Jennifer A HallidayChristel Hendrieckx
Oct 21, 2021·Diabetic Medicine : a Journal of the British Diabetic Association·Hannah ChatwinUNKNOWN Hypo-RESOLVE Consortium

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