Evaluating the safety and efficacy of sodium-restricted/Dietary Approaches to Stop Hypertension diet after acute decompensated heart failure hospitalization: design and rationale for the Geriatric OUt of hospital Randomized MEal Trial in Heart Failure (GOURMET-HF)

American Heart Journal
Jeffrey D WesslerScott L Hummel

Abstract

Heart failure (HF) is a major public health problem affecting predominantly older adults. Nonadherence to diet remains a significant contributor to acute decompensated HF (ADHF). The sodium-restricted Dietary Approaches to Stop Hypertension (DASH/SRD) eating plan reduces cardiovascular dysfunction that can lead to ADHF and is consistent with current HF guidelines. We propose that an intervention that promotes adherence to the DASH/SRD by home-delivering meals will be safe and improve health-related quality of life (QOL) in older adults after hospitalization for ADHF. This is a 3-center, randomized, single-blind, controlled trial of 12-week duration designed to determine the safety and efficacy of home-delivered DASH/SRD-compliant meals in older adults after discharge from ADHF hospitalization. Sixty-six subjects will be randomized in a 1:1 stratified fashion by gender and left ventricular ejection fraction (<50% vs ≥50%). Study subjects will receive either preprepared, home-delivered DASH/SRD-compliant meals or usual dietary advice for 4weeks after hospital discharge. Investigators will be blinded to group assignment, food diaries, and urinary electrolyte measurements until study completion. The primary efficacy end point is th...Continue Reading

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Citations

Jan 7, 2016·Ageing Research Reviews·Alejandro Silva-PalaciosCecilia Zazueta
Nov 26, 2015·Current Opinion in Cardiology·Eloisa Colin-Ramirez, Justin A Ezekowitz
Aug 2, 2016·The Canadian Journal of Cardiology·Hoda Butrous, Scott L Hummel
Mar 8, 2017·The Journal of Clinical Hypertension·Michelle M Y WongJacqui Webster
Nov 7, 2018·JAMA Internal Medicine·Kamal R MahtaniDavid Nunan
Oct 26, 2018·Circulation. Heart Failure·Scott L HummelMathew S Maurer
Mar 17, 2017·Current Treatment Options in Cardiovascular Medicine·Eloisa Colin-RamirezJustin A Ezekowitz
Dec 17, 2020·International Journal of Molecular Sciences·Yash Patel, Jacob Joseph
May 18, 2020·The American Journal of Cardiology·Laura P CohenScott L Hummel

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