PMID: 8598372Mar 1, 1996Paper

Evaluation and scoring of radiotherapy treatment plans using an artificial neural network

International Journal of Radiation Oncology, Biology, Physics
T R WilloughbyI I Rosen

Abstract

The objective of this work was to demonstrate the feasibility of using an artificial neural network to predict the clinical evaluation of radiotherapy treatment plans. Approximately 150 treatment plans were developed for 16 patients who received external-beam radiotherapy for soft-tissue sarcomas of the lower extremity. Plans were assigned a figure of merit by a radiation oncologist using a five-point rating scale. Plan scoring was performed by a single physician to ensure consistency in rating. Dose-volume information extracted from a training set of 511 treatment plans on 14 patients was correlated to the physician-generated figure of merit using an artificial neural network. The neural network was tested with a test set of 19 treatment plans on two patients whose plans were not used in the training of the neural net. Physician scoring of treatment plans was consistent to within one point on the rating scale 88% of the time. The neural net reproduced the physician scores in the training set to within one point approximately 90% of the time. It reproduced the physician scores in the test set to within one point approximately 83% of the time. An artificial neural network can be trained to generate a score for a treatment plan t...Continue Reading

References

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Citations

Apr 5, 2001·International Journal of Radiation Oncology, Biology, Physics·G StarkschallC W Stevens
Nov 21, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Joanna Kazmierska, Julian Malicki
Jan 26, 2005·International Journal of Radiation Oncology, Biology, Physics·Isaac RosenZhongxing Liao
Dec 6, 2003·IEEE Transactions on Bio-medical Engineering·Elpiniki I PapageorgiouPeter P Groumpos
Jul 27, 2004·Physics in Medicine and Biology·Greg BednarzRichard K Valicenti
Jan 23, 2020·The British Journal of Radiology·Issam El NaqaRandall K Ten Haken
Sep 24, 1999·Physics in Medicine and Biology·C G RowbottomM Oldham
Sep 24, 1999·Physics in Medicine and Biology·M T MunleyL B Marks
Aug 26, 2018·Medical Physics·Issam El NaqaRandall Ten Haken
Jul 27, 2021·Physics and Imaging in Radiation Oncology·Matthew FieldLois Holloway

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