PMID: 6103831Mar 1, 1980

Evaluation and treatment of patients with prolactin-secreting pituitary tumors

International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics
J A Fayez, J R Sowers


Six women with secondary amenorrhea and hyperprolactinemia, four of whom had associated galactorrhea, were studied. Four were found to have prolactin-secreting pituitary microadenomas and two had macroadenomas. Suppression of prolactin secretion and stimulation of prolactin, serum growth hormone and thyroid-stimulating hormone secretion were studied, and gonadotropin and adrenocorticotropic hormone reserves were evaluated. The most sensitive techniques available for the diagnosis of pituitary adenomas in patients with amenorrhea and hyperprolactinemia appear to be the measurement of the magnitude of plasma prolactin elevation and hypocycloidal tomography of the sella turcica. The dynamic function tests proved to be of little diagnostic, but of great prognostic, value for patients with small pituitary tumors.


Nov 1, 1977·Obstetrical & Gynecological Survey·W R KeyeR B Jaffe
Jun 15, 1977·American Journal of Obstetrics and Gynecology·R J ChangR B Jaffe
Apr 2, 1977·British Medical Journal·J A WassG M Besser
Oct 1, 1976·The Journal of Clinical Endocrinology and Metabolism·J R SowersC M Baugh
Dec 15, 1976·American Journal of Obstetrics and Gynecology·R H WiebeL G Borchert
Oct 1, 1975·The Journal of Clinical Endocrinology and Metabolism·A E PekaryA F Parlow
Jan 1, 1974·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·J L Vezina, T J Sutton
Sep 1, 1970·The Journal of Clinical Endocrinology and Metabolism·A M LawrenceL Kirsteins

Related Concepts

Adenoma, Trabecular
Postpartum Amenorrhea
Pituitary Function Tests
Pituitary Carcinoma

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