Evaluation, management, and outcome of focal bacterial infections (FBIs) in nontoxic infants under two months of age

Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine
Gurpreet Vidwan, Gary L Geis

Abstract

Well-appearing young infants with focal bacterial infections present to the emergency department (ED) and are often admitted for a sepsis evaluation of blood, urine, and spinal fluid. However, the risk of concomitant systemic infections (CSI) in this population is not well reported, specifically comparing febrile to afebrile infants. We hypothesized that afebrile, well-appearing infants under two months of age with a defined focal bacterial infection on exam have a very low risk of CSI. This retrospective study was conducted at an urban, academic, tertiary care pediatric hospital ED on patients seen from January 2000-December 2005. Eligible infants were less than 60 days of age, well-appearing on exam, and with normal-for-age vital signs who presented with a focal bacterial infection on exam. Exclusion criteria included immunodeficiency, indwelling catheter, previous admission for bacterial infection, or current use of systemic antibiotics. Main study outcome was risk of CSI in febrile and afebrile groups. One hundred ninety seven patients were included in the study population. Of these, 39 were febrile and 158 were afebrile. Four patients had a documented CSI: one case of S. pneumoniae bacteremia and three cases of E. coli uri...Continue Reading

References

Jun 1, 1977·Pediatrics·T R TetzlaffJ D Nelson
May 1, 1988·The Pediatric Infectious Disease Journal·S DollbergD Engelhard
Aug 1, 1986·Clinical Pediatrics·M Walsh, K McIntosh
Dec 1, 1983·American Journal of Diseases of Children·C DeAngelisE Willis
Nov 1, 1994·Journal of Pediatric Surgery·M SamuelM P Nayar
May 1, 1994·American Journal of Surgery·R S SawinJ Cahill
Nov 11, 1993·The New England Journal of Medicine·M D BakerJ R Avner
Jan 1, 1993·The Pediatric Infectious Disease Journal·L A Bailey, N J Waecker
Jan 1, 1993·The Pediatric Infectious Disease Journal·A M Anglada, J M Ceriani Cernadas
Mar 1, 1993·The Journal of Pediatrics·L R Ciarallo, P C Rowe
May 1, 1997·The American Journal of Emergency Medicine·P C FerreraH S Snyder
Mar 11, 1998·Pediatrics·K B Sadow, J M Chamberlain
Apr 2, 1999·Emergency Medicine Clinics of North America·M Slater, S E Krug
Aug 25, 1999·Pediatric Emergency Care·C A NozickaH M Hennes
Aug 2, 2000·Pediatrics·K L McGowanS E Coffin
Aug 29, 2002·Archives of Pediatrics & Adolescent Medicine·Daniel J Isaacman, Bonnie L Burke
Nov 5, 2003·Pediatrics·Jill A HoffmanSheldon L Kaplan
Mar 11, 2004·JAMA : the Journal of the American Medical Association·Robert H PantellRichard C Wasserman
Jun 3, 2004·Pediatrics·Deborah A LevineUNKNOWN Multicenter RSV-SBI Study Group of the Pediatric Emergency Medicine Collaborative Research Committee of the American Academy
Sep 3, 2004·The Journal of Pediatrics·Kenneth B Roberts
Sep 13, 2005·International Journal of Pediatric Otorhinolaryngology·Waheeb SakranAriel Koren

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Citations

Nov 4, 2015·Hospital Pediatrics·Gabrielle HesterRajendu Srivastava
Dec 14, 2018·Journal of the Pediatric Infectious Diseases Society·Laura Chappell-CampbellAlan R Schroeder
Aug 22, 2018·Pediatric Emergency Care·Dana M ForadoriSowdhamini S Wallace
Jul 15, 2021·Journal of Child Neurology·Darrah N HaffnerNathalie L Maitre

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