Evaluation of ¹⁸F-FDG PET/MRI, ¹⁸F-FDG PET/CT, MRI, and CT in whole-body staging of recurrent breast cancer

European Journal of Radiology
Lino Morris SawickiSonja Kinner

Abstract

To compare the diagnostic performance of (18)F-fluordesoxyglucose positron emission tomography/magnetic resonance imaging ((18)F-FDG PET/MRI) with (18)F-FDG PET/computed tomography ((18)F-FDG PET/CT), MRI, and CT in whole-body staging of recurrent breast cancer. Twenty-one consecutive patients (age 59.4 ± 11.5 years, range 38.5-76.9 years; 20 female, 1 male) with suspected breast cancer recurrence underwent a clinically indicated (18)F-FDG PET/CT and subsequently a (18)F-FDG PET/MRI examination in a single injection protocol (mean injected activity: 257 ± 44 MBq (18)F-FDG). Each (18)F-FDG PET/MRI, (18)F-FDG PET/CT, as well as the CT component of PET/CT (CTPET/CT) and MR images of PET/MRI (MRIPET/MRI) were separately evaluated by two radiologists regarding lesion count, lesion localization, and lesion categorization (benign/malignant). The reference standard was based on histopathological results as well as prior and follow-up imaging. A Wilcoxon test assessed differences in SUVmax between (18)F-FDG PET/MRI and (18)F-FDG PET/CT. Correlation of SUVmax between (18)F-FDG PET/MRI and (18)F-FDG PET/CT was calculated using Pearson's correlation coefficient. Interobserver agreement on dignity ratings was evaluated using Cohen's kappa. ...Continue Reading

References

Dec 25, 2003·JAMA : the Journal of the American Medical Association·Gerald AntochStefan G Ruehm
Nov 1, 2005·European Journal of Nuclear Medicine and Molecular Imaging·Mitsuaki TatsumiRichard L Wahl
Dec 13, 2005·International Journal of Cancer. Journal International Du Cancer·Lene MellemkjaerPaul Brennan
Jan 27, 2006·Radiology·Gustav K von SchulthessThomas F Hany
Sep 5, 2006·European Radiology·Gerwin P SchmidtAndrea Baur-Melnyk
Aug 8, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·William F AndersonRuth M Pfeiffer
Oct 9, 2007·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Conor D Collins
Mar 22, 2008·Annals of Oncology : Official Journal of the European Society for Medical Oncology·S MahnerJ Dose-Schwarz
Dec 8, 2009·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·T S AukemaR A Valdés Olmos
Nov 12, 2010·Breast Cancer Research : BCR·Li Ma
Feb 26, 2011·International Journal of Cancer. Journal International Du Cancer·Jacques FerlayDonald Maxwell Parkin
May 15, 2012·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Christian BuchbenderGerald Antoch
Jan 25, 2013·AJR. American Journal of Roentgenology·Danny L CostantiniMartin Charron
Jan 31, 2013·European Journal of Nuclear Medicine and Molecular Imaging·Gang ChengAbass Alavi
Feb 8, 2014·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Philipp HeuschTill A Heusner
Mar 22, 2014·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Isabel RauscherAmbros J Beer

❮ Previous
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Citations

Aug 19, 2016·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·D L BaileyT Beyer
Mar 30, 2017·Annals of Nuclear Medicine·Amit SingnurkarUr Metser
Mar 7, 2017·European Journal of Radiology·Axel WetterLale Umutlu
Oct 7, 2018·Journal of Magnetic Resonance Imaging : JMRI·Akshat C PujaraAmy N Melsaether
Mar 9, 2018·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Koosha PaydaryAbass Alavi
Jul 4, 2019·European Journal of Nuclear Medicine and Molecular Imaging·Anni MorsingPoul Flemming Høilund-Carlsen
Apr 26, 2020·European Journal of Nuclear Medicine and Molecular Imaging·Nils Martin BruckmannChristian Buchbender
Jul 30, 2018·European Journal of Nuclear Medicine and Molecular Imaging·Julian KirchnerLale Umutlu
May 24, 2017·European Journal of Nuclear Medicine and Molecular Imaging·Julian KirchnerLale Umutlu
Dec 15, 2018·Head & Neck·Julian KirchnerVerena Ruhlmann
Feb 6, 2017·European Journal of Nuclear Medicine and Molecular Imaging·Julian KirchnerLale Umutlu
Dec 3, 2020·Physics in Medicine and Biology·Ciprian Catana
Jun 9, 2018·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Bert-Ram SahPatrick Veit-Haibach
Dec 7, 2019·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Ole MartinLale Umutlu
Jun 7, 2021·Seminars in Radiation Oncology·Ali PirastehIvan Pedrosa
Aug 17, 2021·Radiologic Clinics of North America·Amy M Fowler, Steve Y Cho

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