Evaluation of 2D multiband EPI imaging for high-resolution, whole-brain, task-based fMRI studies at 3T: Sensitivity and slice leakage artifacts

NeuroImage
Nick ToddNikolaus Weiskopf

Abstract

Functional magnetic resonance imaging (fMRI) studies that require high-resolution whole-brain coverage have long scan times that are primarily driven by the large number of thin slices acquired. Two-dimensional multiband echo-planar imaging (EPI) sequences accelerate the data acquisition along the slice direction and therefore represent an attractive approach to such studies by improving the temporal resolution without sacrificing spatial resolution. In this work, a 2D multiband EPI sequence was optimized for 1.5mm isotropic whole-brain acquisitions at 3T with 10 healthy volunteers imaged while performing simultaneous visual and motor tasks. The performance of the sequence was evaluated in terms of BOLD sensitivity and false-positive activation at multiband (MB) factors of 1, 2, 4, and 6, combined with in-plane GRAPPA acceleration of 2× (GRAPPA 2), and the two reconstruction approaches of Slice-GRAPPA and Split Slice-GRAPPA. Sensitivity results demonstrate significant gains in temporal signal-to-noise ratio (tSNR) and t-score statistics for MB 2, 4, and 6 compared to MB 1. The MB factor for optimal sensitivity varied depending on anatomical location and reconstruction method. When using Slice-GRAPPA reconstruction, evidence of ...Continue Reading

References

Sep 1, 1991·Journal of Magnetic Resonance Imaging : JMRI·J E Bishop, D B Plewes
Jun 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·T LoennekerJ Hennig
Feb 13, 2001·Journal of Magnetic Resonance Imaging : JMRI·D J LarkmanG Ehnholm
May 29, 2002·NeuroImage·Karl J FristonJohn Ashburner
Jul 12, 2002·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·David A FeinbergVan J Wedeen
Feb 22, 2005·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Felix A BreuerPeter M Jakob
Jun 16, 2005·NeuroImage·John Ashburner, Karl J Friston
Feb 9, 2010·NeuroImage·Benedikt A PoserM Barth
May 1, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Steen MoellerKamil Ugurbil
Aug 23, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Kawin SetsompopLawrence L Wald
Jan 28, 2012·NeuroImage·David A Feinberg, Essa Yacoub
Jan 31, 2012·NeuroImage·Fa-Hsuan LinJohn W Belliveau
Jul 24, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Antoine LuttiNikolaus Weiskopf
Mar 12, 2013·Journal of Magnetic Resonance·David A Feinberg, Kawin Setsompop
May 25, 2013·NeuroImage·Stephen M SmithWU-Minn HCP Consortium
Aug 22, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Stephen F CauleyKawin Setsompop
Nov 26, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Yunjie TongBlaise deB Frederick
Jun 24, 2014·Human Brain Mapping·Yunjie Tong, Blaise deB Frederick
Nov 8, 2014·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Benjamin ZahneisenBenedikt A Poser

Citations

Jun 10, 2018·Human Brain Mapping·Nadège CorbinMartina F Callaghan
Jan 6, 2018·AJNR. American Journal of Neuroradiology·E LapointeA Rauscher
Feb 10, 2018·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·W Scott HogeJonathan R Polimeni
Feb 11, 2018·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Uten YarachOliver Speck
Sep 20, 2018·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Amy R McDowell, David W Carmichael
Sep 20, 2018·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Bruno RiemenschneiderJürgen Hennig
Dec 19, 2018·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Shiori AmemiyaOsamu Abe
Mar 19, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Suhyung ParkDavid A Feinberg
Apr 25, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Chenxi HuR Todd Constable
Jun 21, 2020·Journal of Magnetic Resonance Imaging : JMRI·Steen MoellerKamil Ugurbil
Aug 18, 2020·Brain Topography·Xiaojin LiuRuiwang Huang
Dec 10, 2016·Frontiers in Neuroscience·Suzanne T WittMaria Engström
Mar 23, 2019·Nature Communications·Wiktor OlszowyGuy B Williams
Jun 15, 2019·Brain : a Journal of Neurology·Anne MaassWilliam J Jagust
Jan 29, 2019·Frontiers in Neuroscience·Peter ZeidmanMartina F Callaghan
Oct 2, 2018·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Christoph RettenmeierV Andrew Stenger
Mar 7, 2020·Brain Structure & Function·Carolyn Beth McNabbTom Johnstone
Jul 25, 2019·ELife·Guangyu ZhouChristina Zelano
Mar 3, 2020·Frontiers in Human Neuroscience·Robert J GougeletDaniel E Callan
Mar 8, 2020·Brain Topography·Joseph C C ChenSuresh D Muthukumaraswamy
Jan 19, 2018·Brain and Neuroscience Advances·Nitin Williams, Richard N Henson
Nov 20, 2020·Journal of Magnetic Resonance Imaging : JMRI·Alexander D CohenYang Wang
Feb 9, 2019·NeuroImage·Jingyuan E ChenGary H Glover
Feb 11, 2021·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Omer Burak DemirelMehmet Akçakaya
Jan 28, 2021·Social Cognitive and Affective Neuroscience·E Jolly, L J Chang
Mar 8, 2021·Cerebral Cortex·Philipp KuhnkeGesa Hartwigsen
Mar 22, 2021·NeuroImage·Benjamin B RiskDeqiang Qiu
Mar 27, 2021·Frontiers in Neuroscience·Rodolfo Abreu, João Valente Duarte
Mar 22, 2021·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Bruno RiemenschneiderJürgen Hennig

Related Concepts

Brain
Functional Cerebral Localization
Optical Image Reconstruction
Photic Stimulation
Visual Perception
Reproducibility of Results
Morphologic Artifacts
Echo-Planar MR Tomography
Signal-To-Noise Ratio
Diagnostic Imaging

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Lipidomics & Rhinovirus Infection

Lipidomics can be used to examine the lipid species involved with pathogenic conditions, such as viral associated inflammation. Discovered the latest research on Lipidomics & Rhinovirus Infection.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Torsion Dystonia

Torsion dystonia is a movement disorder characterized by loss of control of voluntary movements appearing as sustained muscle contractions and/or abnormal postures. Here is the latest research.

Generating Insulin-Secreting Cells

Reprogramming cells or using induced pluripotent stem cells to generate insulin-secreting cells has significant therapeutic implications for diabetics. Here is the latest research on generation of insulin-secreting cells.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Epigenome Editing

Epigenome editing is the directed modification of epigenetic marks on chromatin at specified loci. This tool has many applications in research as well as in the clinic. Find the latest research on epigenome editing here.

© 2021 Meta ULC. All rights reserved