PMID: 6725603May 1, 1984Paper

Evaluation of a commercial antibody capture enzyme immunoassay for the detection of rubella specific IgM

Journal of Clinical Pathology
J Hodgson, P Morgan-Capner

Abstract

A commercial M antibody capture ELISA kit ( Rubenz M) for the detection of rubella specific IgM was evaluated in comparison with M antibody capture radioimmunoassay. A total of 248 sera were evaluated, including sera from cases of primary postnatal rubella, congenital rubella, infectious mononucleosis, and sera which contained rheumatoid factor. No false positive results were obtained but two high positive sera gave Rubenz M values which were below the value recommended as indicative of a positive result. We therefore propose changes in the criteria used for assessing the significance of the results obtained. These changes improve the accuracy of the assay without loss of specificity.

References

Aug 1, 1978·The Journal of Infectious Diseases·K GranforsP Toivanen
Jan 1, 1982·Journal of Medical Virology·M Isaac, R A Payne
Jun 1, 1983·The Journal of Hygiene·P Morgan-CapnerJ E Mace
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Nov 1, 1980·Journal of Clinical Pathology·P Morgan-CapnerJ R Pattison
Apr 1, 1981·The Journal of Hygiene·P P MortimerU Schilt

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Citations

Sep 1, 1991·Journal of Virological Methods·P CordobaM Zapata
May 12, 2004·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Graham A TipplesSamuel Ratnam
Feb 1, 1985·Journal of Clinical Pathology·H Cubie, E Edmond
Apr 1, 1986·The Journal of Hygiene·D J NokesM J Anderson

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