Evaluation of a disposable device for the measurement of haemoglobin A1c in dogs

The Veterinary Record
B CatchpoleR J Scaramuzzi

Abstract

A disposable device designed for measuring glycated haemoglobin (hba1c) in human blood was evaluated for use in dogs. edta blood samples were collected from 50 normoglycaemic dogs, 10 dogs suffering from anaemia and 112 diabetic dogs. hba1c was measured in all the dogs except for five of the diabetic animals, in which the concentrations were above the range of the device, that is, more than 13 per cent, and two of the anaemic dogs, in which they were below its limit of detection, that is less than 3 per cent. The diabetic dogs had higher hba1c values (range 4.9 to >13 per cent, median 9.3 per cent) than the normoglycaemic dogs (range 3.7 to 5.6 per cent, median 4.7 per cent). In the anaemic dogs the values were significantly lower (range <3.0 per cent to 5.2 per cent, median 3.5 per cent) than in the normoglycaemic dogs. There was a good correlation (R(2)=0.48) between the measurements obtained with the device and the measurements obtained with a system already validated for use in dogs.

References

Jan 1, 1992·Veterinary Research Communications·A L Jensen
May 1, 1993·Journal of Veterinary Internal Medicine·C E ReuschR Vochezer
Dec 20, 2002·The Journal of Small Animal Practice·L J DavisonB Catchpole
Dec 25, 2003·Diabetes Care·David E GoldsteinUNKNOWN American Diabetes Association

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Citations

Apr 8, 2017·Veterinary Clinical Pathology·Anne F GoemansIan K Ramsey
Feb 20, 2019·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Na-Yon KimYongbaek Kim
Feb 27, 2020·American Journal of Veterinary Research·Francesca Del BaldoFederico Fracassi

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