Evaluation of a hepatitis C clinical care coordination programme's effect on treatment initiation and cure: A surveillance-based propensity score matching approach

Journal of Viral Hepatitis
R DemingFabienne Laraque

Abstract

Hepatitis C (HCV) is a viral infection that if left untreated can severely damage the liver. Project INSPIRE was a 3 year HCV care coordination programme in New York City (NYC) that aimed to address barriers to treatment initiation and cure by providing patients with supportive services and health promotion. We examined whether enrolment in Project INSPIRE was associated with differences in HCV treatment and cure compared with a demographically similar group not enrolled in the programme. INSPIRE participants in 2015 were matched with a cohort of HCV-infected persons identified in the NYC surveillance registry, using full optimal matching on propensity scores and stratified by INSPIRE enrolment status. Conditional logistic regression was used to assess group differences in the two treatment outcomes. Two follow-up sensitivity analyses using individual pair-matched sets and the full unadjusted cohort were also conducted. Treatment was initiated by 72% (790/1130) of INSPIRE participants and 36% (11 960/32 819) of study-eligible controls. Among initiators, 65% (514/790) of INSPIRE participants compared with 47% (5641/11 960) of controls achieved cure. In the matched analysis, enrolment in INSPIRE increased the odds of treatment in...Continue Reading

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Citations

Feb 6, 2020·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Czarina N BehrendsBruce R Schackman
Aug 31, 2019·Journal of Healthcare Risk Management : the Journal of the American Society for Healthcare Risk Management·Kyle FlueggeAnn Winters
Mar 9, 2021·Hepatology Communications·Nancy Yang, Andrew Muir
Mar 9, 2021·Hepatology Communications·Arpan A PatelPonni V Perumalswami
Aug 2, 2021·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Brooke WyattAndrea D Branch

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