Evaluation of a new artificial tear formulation for the management of tear film stability and visual function in patients with dry eye.

Clinical Ophthalmology
Gail TorkildsenJoseph B Ciolino

Abstract

Artificial tears are the first line of therapy for dry eye disease (DED) and are also the most frequently used treatment approach for this common condition. Despite this, there are few published studies that directly compare the effectiveness of different drop preparations, especially those formulated specifically for dry eye. In this study, we tested a new artificial tear product, Rohto® Dry-Aid™, for its ability to relieve the signs and symptoms of DED. The study used a second drop, Systane® Ultra, as a positive comparator. This was a prospective, single-center, open-label, parallel-group study comparing the effects of the two products when used continuously over ~30 days (Clinical Trials registration number NCT03183089). Subjects were randomly assigned to one of the two test groups and were monitored 2 and 4 weeks after enrollment. Efficacy endpoints included ocular staining, visual function, and ocular discomfort. Treatment groups had similar ocular staining and ocular comfort scores, and both showed statistically significant ocular discomfort score improvement. Subjects in the Rohto group reported significant improvements in visual tasking activities such as watching television and driving at night. There was also a tenden...Continue Reading

Citations

Jul 28, 2019·Pathogens·María Reyes-BatlleJacob Lorenzo-Morales
Oct 28, 2019·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Windsor Wen-Jin ChaoHsiao-Ming Chao
Jun 18, 2021·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Renee GarofaloHoward Ketelson

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Software Mentioned

Systane
Rohto

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