Evaluation of a new GPU-enabled VMAT multi-criteria optimisation plan generation algorithm

Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists
Myles SpaldingTrent Aland

Abstract

To evaluate the new Varian, graphical processing unit (GPU)-enabled, volumetric-modulated arc therapy (VMAT) multi-criteria optimisation (MCO) tool for both its dosimetric accuracy and calculation time. This is a new capability within V16.0 and greater of the Varian Eclipse treatment planning system that allows VMAT optimisation and dose calculation using the GPU (termed GPU-VMAT). In versions prior to V16.0 VMAT multi-criteria optimisation calculations were only possible using central processing unit (CPU) (termed CPU-VMAT) and Hybrid-VMAT (H-VMAT). The H-VMAT method breaks down the VMAT plan into IMRT fields which utilised GPU calculations. The study consisted of a cohort of 50 patients representing a range of anatomical treatment sites; bladder (5), brain (5), gynae (5), head & neck (5), lung (7), mediastinum (7) prostate (4), oesophagus (7) and rectum (5). Each case was planned to that of a clinical standard (Base) which was compared to a CPU-VMAT, GPU-VMAT and H-VMAT approaches. The study analysed dose to organ at risk (OAR) and target coverage, plan calculation time data and plan complexity through monitor unit (MU) for each approach. Negligible dosimetric differences were found between the CPU-VMAT, GPU-VMAT and H-VMAT a...Continue Reading

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