PMID: 9431954Feb 12, 1998Paper

Evaluation of a rapid immunochromatographic test for diagnosis of dengue virus infection

Journal of Clinical Microbiology
D W VaughnP L Devine

Abstract

A rapid (<7-min) immunochromatographic test for immunoglobulin M (IgM) and IgG antibodies to dengue viruses was evaluated by using hospital admission and discharge sera from 124 patients. The reference laboratory diagnosis was based on the results of virus isolation, hemagglutination-inhibition assay (HAI), and enzyme immunoassay (EIA). By the standard assays, patients experienced primary dengue virus infection (n = 30), secondary dengue virus infection (n = 48), Japanese encephalitis (JE) virus infection (n = 20), or no flavivirus infection (n = 26). The rapid test demonstrated 100% sensitivity in the diagnosis of dengue virus infection and was able to distinguish between primary and secondary dengue virus infections through the separate determinations of IgM and IgG. For all patients with primary dengue virus infection a positive test for IgM to dengue virus and a negative test for IgG to dengue virus were obtained, whereas for 46 of 48 patients (96%) with secondary dengue virus infection, a positive test for IgG to dengue virus with or without a positive test for IgM to dengue virus was obtained. The remaining two patients with secondary dengue virus infection had positive IgM test results and negative IgG test results. Furt...Continue Reading

References

May 1, 1977·The American Journal of Tropical Medicine and Hygiene·T T Kuberski, L Rosen
Jun 1, 1992·Acta Paediatrica Japonica; Overseas Edition·S K Hendarto, S R Hadinegoro
Jun 1, 1991·Journal of Virological Methods·G KunoD J Gubler
Apr 1, 1989·The American Journal of Tropical Medicine and Hygiene·B L InnisC H Hoke
Jul 1, 1985·The American Journal of Tropical Medicine and Hygiene·L Rosen, D A Shroyer
Oct 1, 1985·Journal of Virological Methods·G KunoN S Santiago de Weil
Jan 1, 1985·Intervirology·E G WestawayD W Trent
Jan 1, 1988·The American Journal of Tropical Medicine and Hygiene·D S BurkeR M Scott
Nov 1, 1974·The American Journal of Tropical Medicine and Hygiene·L Rosen, D Gubler
Jan 1, 1994·Microbiology and Immunology·Y MakinoT Fukunaga
Mar 29, 1994·Proceedings of the National Academy of Sciences of the United States of America·T P Monath
Mar 1, 1996·The American Journal of Tropical Medicine and Hygiene·L C LumF Harun
Nov 1, 1996·Clinical and Diagnostic Virology·S K LamV Vorndam
Aug 1, 1997·The Journal of Infectious Diseases·D W VaughnA Nisalak
Sep 1, 1958·The American Journal of Tropical Medicine and Hygiene·D H CLARKE, J CASALS

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Citations

Nov 1, 2001·Clinical and Diagnostic Laboratory Immunology·A J CuzzubboP L Devine
Jul 10, 2004·Clinical and Diagnostic Laboratory Immunology·Pei-Yun Shu, Jyh-Hsiung Huang
Sep 28, 2007·Current Microbiology·Anita ChakravartiManisha Jain
Feb 5, 2011·The American Journal of Tropical Medicine and Hygiene·Richard G JarmanRobert V Gibbons
Nov 20, 2014·Vector Borne and Zoonotic Diseases·Ali M MessengerDana A Focks
Nov 4, 2000·Clinical and Diagnostic Laboratory Immunology·J GroenA D Osterhaus
Apr 1, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Stuart D BlacksellNicholas P J Day
Jan 9, 2007·Tropical Medicine & International Health : TM & IH·Adam L CohenTamara L Fisk
Aug 9, 2001·Transactions of the Royal Society of Tropical Medicine and Hygiene·A L CorwinK R Porter
May 2, 2003·Acta Clinica Belgica·E BottieauA Van Gompel
Dec 20, 2012·The Pediatric Infectious Disease Journal·Wen-Pin LaiChih-Hung Chang
May 10, 2020·Clinical Chemistry and Laboratory Medicine : CCLM·Shaun S TanSunil K Sethi
Nov 5, 2002·Clinical and Diagnostic Laboratory Immunology·Rémi N Charrel, Xavier de Lamballerie
Jul 8, 2011·The American Journal of Tropical Medicine and Hygiene·Nicolas SennWilliam John Hannan McBride
Jan 4, 2001·Clinical and Diagnostic Laboratory Immunology·H S ShinT R Heo
Nov 11, 2003·Clinical and Diagnostic Laboratory Immunology·Susana VázquezMaría G Guzmán
Jan 5, 2000·Clinical and Diagnostic Laboratory Immunology·S J WuC G Hayes
Mar 11, 2003·Clinical and Diagnostic Laboratory Immunology·Angel BalmasedaEva Harris
Mar 7, 2002·Journal of Virological Methods·Tomohiko TakasakiIchiro Kurane
Jul 3, 1999·Clinical and Diagnostic Laboratory Immunology·S L Branch, P N Levett
Nov 18, 1998·Journal of Clinical Microbiology·A J CuzzubboP L Devine
Jul 3, 1998·Journal of Clinical Microbiology·T SolomonM J Cardosa
Aug 17, 1999·Journal of Clinical Microbiology·C M ParryJ J Farrar
Jul 17, 1998·Clinical Microbiology Reviews·D J Gubler
Jan 9, 2009·Annals of Clinical Microbiology and Antimicrobials·Bharat M PokhrelJanak Koirala

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