Evaluation of Abbott's BurstDR stimulation device for the treatment of chronic pain

Expert Review of Medical Devices
Timothy R DeerJason E Pope

Abstract

Burst stimulation, as described by DeRidder, is a novel waveform made up of closely spaced, high-frequency electrical impulses delivered in packets, which are followed by a quiescent period or interburst interval. Electrically generated burst waveforms were initially designed to treat neural pathology in the auditory cortex and were later applied to the spinal cord through spinal cord stimulation (SCS) devices to treat chronic pain states. When Burst stimulation is applied to the spinal cord, the impulses travel to the thalamus and then diverge, targeting both the somatosensory cortex and the limbic system where they treat both the sensory, affective and attentional components of neuropathic pain. Areas covered: Literature examining clinical and basic research findings with the application of Burst stimulation to pathologically active central neural tissue was found using bibliographic databases including PubMed, Medline, Cochrane, Embase and Google Scholar. Expert commentary: Burst stimulation offers a salvage strategy for failed tonic spinal cord stimulation (tSCS), thus improving both quality of life and cost-effectiveness of SCS by reducing explant rates. The goal of this therapy is to use more than one waveform in the same...Continue Reading

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Citations

Oct 5, 2018·Neuromodulation : Journal of the International Neuromodulation Society·Kerolos R Yousef, Brian R Monroe
Nov 21, 2018·Neuromodulation : Journal of the International Neuromodulation Society·Jan VesperTony Van Havenbergh
Jun 4, 2019·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Terje KirketeigTimothy Deer
Jun 4, 2019·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Krishnan ChakravarthyTimothy Deer
Jun 4, 2019·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Krishnan ChakravarthyRobert Levy
Jun 3, 2021·Neuromodulation : Journal of the International Neuromodulation Society·Mohammad SaberChristopher P Pawela

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