Evaluation of accordance of antibiotics package size with recommended treatment duration of guidelines for sore throat and urinary tract infections

Antimicrobial Resistance and Infection Control
Doris RusicSinisa Tomic

Abstract

The aim of this study was to investigate whether marketed antibiotics package sizes are in accordance with treatment durations recommended in guidelines for prescribing antibiotics in sore throat and urinary tract infections. National drug database was searched with limitation to Antibacterials for systemic use. Formulations which did not have pre-specified dosage unit by the manufacturer were excluded (e.g. powders for oral solutions). The final list contained 94 drugs with 23 different active substances. This list was then cross-referenced with selected antimicrobial prescribing guidelines provided by Intersectoral Society for Antibiotic Resistance Control (ISKRA), National Institute for Health and Care Excellence (NICE) and The Infectious Diseases Society of America (IDSA). Seven packages matched ISKRA guidelines on sore throat while 16 were mismatched. Considering drug packages under reimbursement, 3 matched ISKRA guidelines and 8 were mismatched. Only 3 packages matched IDSA guidelines for comparable indications, and 18 were mismatched. When considering NICE guidelines there were 5 mismatched and only one package that was in accordance with the guidelines. ISKRA guidelines for urinary tract infections matched 23 packages a...Continue Reading

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Citations

May 10, 2020·Antimicrobial Resistance and Infection Control·Julia FüriJulia Anna Bielicki
Oct 15, 2020·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Doris RusicSinisa Tomic
Jul 28, 2021·The Journal of Antimicrobial Chemotherapy·Robin BruyndonckxUNKNOWN ESAC-Net study group

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Methods Mentioned

BETA
pharmacotherapy

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