Evaluation of Acellular Dermal Matrix Efficacy in Prosthesis-Based Breast Reconstruction

Plastic and Reconstructive Surgery
Nikhil SobtiEric C Liao

Abstract

Although many studies have examined the safety of acellular dermal matrix in immediate prosthetic breast reconstruction, few studies have evaluated efficacy. This study examined initial tissue expander fill volume as a marker of efficacy, comparing patients after staged prosthetic breast reconstruction assisted with acellular dermal matrix versus breast reconstruction not assisted with acellular dermal matrix. Number of fill visits and time interval to implant exchange were examined as secondary endpoints. An institutional review board-approved retrospective chart review was conducted to identify consecutive staged prosthetic reconstruction cases over 12 years. Mean initial tissue expander fill volume was significantly higher in the acellular dermal matrix group compared with the non-acellular dermal matrix group (180.8 ± 150.0 versus 45.8 ± 74.4; p = 0.00). Normalizing for final implant size, the acellular dermal matrix group exhibited significantly higher perioperative fill (0.33 ± 0.24 versus 0.11 ± 0.16; p = 0.00). A collinear trend was observed between acellular dermal matrix use and direct-to-implant reconstruction procedures during the study period. These results suggest that acellular dermal matrix use is more efficacio...Continue Reading

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Citations

Dec 6, 2018·Plastic and Reconstructive Surgery·Yiye OuyangChunjun Liu
Oct 9, 2019·Plastic and Reconstructive Surgery. Global Open·Gabriel M KleinDuc T Bui
Mar 22, 2019·Molecular Medicine Reports·Yan-Ling QiuXu-Qian Liu
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Jun 21, 2020·Breast Cancer Research and Treatment·Michelle SpechtEric C Liao
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Mar 18, 2021·Plastic and Reconstructive Surgery. Global Open·Keith SweitzerErgun Kocak
Aug 18, 2020·Plastic and Reconstructive Surgery. Global Open·Julian Diaz-AbeleEdward W Buchel
Jul 28, 2021·Plastic and Reconstructive Surgery·Ziying Zhang, Minqiang Xin

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