Evaluation of acute and chronic MRI features of sacroiliitis in asymptomatic primary hyperparathyroid patients

Clinical Rheumatology
Mehmet Engin TezcanMehmet Sargin

Abstract

Asymptomatic primary hyperparathyroidism (PHPT) is characterized with autonomous overproduction of parathyroid hormone without signs or symptoms associated with hyperparathyroidism. Before symptoms become obvious, PHPT may affect structures like sacroiliac joints, which consist of bone. So, in the asymptomatic PHPT patients, structural and inflammatory changes in sacroiliac joints may lead to confusion during diagnosis workup of axial spondyloarthropathy. In this study, we evaluated active and chronic sacroiliac magnetic resonance imaging (MRI) changes relevant to sacroiliitis in the patients with asymptomatic PHPT and interpreted bone marrow edema within the scope of Assessment of SpondyloArthritis International Society-Outcome Measures in Rheumatology Clinical Trials (ASAS-OMERACT) criteria. Forty-nine patients with asymptomatic PHPT, 26 patients with newly diagnosed axial spondyloarthropathy (SpA), and 37 healthy controls were enrolled. All subjects were evaluated by sacroiliac MRI for four active (bone marrow edema, enthesitis, capsulitis, and synovitis) and four chronic (subchondral sclerosis, subchondral/periarticular erosions, periarticular fat deposition, and bony bridges/ankylosis) lesions relevant to sacroiliitis. Bon...Continue Reading

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Citations

Feb 23, 2020·Journal of Clinical Medicine·Sebastian F BaumbachJan Leipe
Feb 24, 2021·Scientific Reports·Virginie KreutzingerKatharina Ziegeler
May 11, 2021·Frontiers in Medicine·António Proença CaetanoPedro M Machado

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