Evaluation of adult celiac disease from a tertiary reference center: a retrospective analysis

Revista da Associação Médica Brasileira
Omer Burcak Binicier, Ferahnaz Tosun

Abstract

It has been observed that celiac disease (CD) is not restricted to a single type characterized by diarrhea but also has atypical, asymptomatic (silent), and latent forms. The prevalence of this autoimmune disease, which affects approximately 1% of the world, is estimated to be around 3%, including atypical and asymptomatic cases. In our study, we aimed to evaluate adult celiac patients. Between December 2008-2015, patients diagnosed with CD over the age of 18 years old were included in the study. Patients' symptoms at admission, frequency and type of anemia, transaminase levels, and celiac antibody positivity, and autoimmune diseases diagnosed at follow up were evaluated retrospectively. Of 195 patients, 151 (77.4%) were female. The mean age of the patients was 35.73 ± 12.19 years (range, 18-71 years). A hundred patients (51.3%) had gastrointestinal symptoms. At the time of admission, 118 patients (60.5%) had anemia, and 52 (26.7%) had hypertransaminasemia. During the mean follow-up period of 58 months (36-120 months), 84 (43.1%) of the patients presented at least one autoimmune disease, and this rate was 96.6% in individuals diagnosed above the age of 50 years. In adult CD, resistant anemia, dyspepsia, and hypertransaminasemia...Continue Reading

References

Feb 1, 1994·European Journal of Endocrinology·P CollinA Pasternack
Aug 1, 1997·Human Molecular Genetics·R S HoulstonM F Stratton
Mar 3, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M T BardellaR De Franchis
Apr 11, 2002·European Journal of Gastroenterology & Hepatology·William Dickey
Sep 5, 2002·Nature Reviews. Immunology·Ludvig M Sollid
May 14, 2003·Digestive Diseases and Sciences·Robert D ZipserElaine Monarch
Apr 22, 2005·Scandinavian Journal of Gastroenterology·Maria Teresa BardellaLuigia Prampolini
Jul 19, 2005·Medical Hypotheses·Mario Peláez-LunaGuillermo Robles-Díaz
Dec 13, 2006·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Jonas F LudvigssonScott M Montgomery
Jul 20, 2007·American Journal of Hematology·Jason W HarperPeter H R Green
Sep 17, 2013·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Peter D MooneyDavid S Sanders
Aug 26, 2015·Nature Reviews. Gastroenterology & Hepatology·Knut E A Lundin, Cisca Wijmenga
Apr 11, 2017·Geriatrics & Gerontology International·Çağdaş KalkanIrfan Soykan
Jun 18, 2017·The American Journal of Medicine·Marco A PaezMukund Venu
Oct 28, 2017·European Journal of Gastroenterology & Hepatology·Louise GrodeCecilia H Ramlau-Hansen
Sep 28, 2018·The Turkish Journal of Gastroenterology : the Official Journal of Turkish Society of Gastroenterology·Gönül Çaltepe

❮ Previous
Next ❯

Citations

Jun 3, 2021·Nutrients·Valentina TalaricoMarco Bertini

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Related Papers

Gastroenterología y hepatología
José María HuguetEnrique Medina
Rheumatology International
Paola CaramaschiDomenico Biasi
São Paulo Medical Journal = Revista Paulista De Medicina
Aline VenturaJanaína Luz Narciso-Schiavon
Indian Pediatrics
Santosh Kumar Mittal, Malobika Bhattacharya
© 2021 Meta ULC. All rights reserved