Evaluation of an automated seed loader for seed calibration in prostate brachytherapy

Journal of Applied Clinical Medical Physics
Shuying WanL John Schreiner

Abstract

Automated seed loaders for permanent prostate implants are now commercially available. Besides improved radiation safety, these systems offer seed assay capability and ease of needle loading, making preplanned as well as intra-operative implant procedures more time-efficient. The Isoloader (Mentor Corp., CA) uses individual I125 seeds (SL-125 ProstaSeed) loaded in up to 199 chambers inside a shielded cartridge. The unit performs seed counting and calibration using a builtin solid-state detector. In order to evaluate the reproducibility and accuracy of the calibration process, two test cartridges were measured with the Isoloader itself and compared with a well-type ionization chamber (HDR-1000Plus, Standard Imaging). The air kerma strength measurements for all seeds using the Isoloader had a standard deviation of about 2.7%. For the eight seeds assayed more intensively using both the Isoloader and well chamber, the standard deviations of the measurements for each seed were in the range of 0.8% to 2.8% and 0.6% to 1.3%, respectively. The variation in the Isoloader calibration is attributed to small detector solid angle and bead geometry within seed capsules (verified by radiographs). The reproducibility of the air kerma strength ...Continue Reading

References

Jan 1, 1992·International Journal of Radiation Oncology, Biology, Physics·S J GoetschB R Thomadsen
Jul 1, 1996·Physics in Medicine and Biology·R J MeilerK H Shin
May 8, 2001·Medical Physics·B H HeintzJ M Hevezi
Oct 4, 2003·Clinical Oncology : a Journal of the Royal College of Radiologists·L Potters
Mar 2, 2005·Journal of Applied Clinical Medical Physics·Janelle MorrierLuc Beaulieu

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Methods Mentioned

BETA
X‐ray

Software Mentioned

Isoloader
IsoCartridge
Mentor Isoloader
MATLAB

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