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Evaluation of an improved branch-site likelihood method for detecting positive selection at the molecular level

Molecular Biology and Evolution

Aug 19, 2005

Jianzhi ZhangZiheng Yang

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Abstract

Detecting positive Darwinian selection at the DNA sequence level has been a subject of considerable interest. However, positive selection is difficult to detect because it often operates episodically on a few amino acid sites, and the signal may be masked by negative selection. Several ...read more

Mentioned in this Paper

In Silico
Likelihood Functions
Sense Codon
Codon Genus
Codon (Nucleotide Sequence)
Bayesian Prediction
Negative Selection
Positive Selection
Amino Acid [EPC]
Evolution, Molecular
2
741
Paper Details
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Evaluation of an improved branch-site likelihood method for detecting positive selection at the molecular level

Molecular Biology and Evolution

Aug 19, 2005

Jianzhi ZhangZiheng Yang

PMID: 16107592

DOI: 10.1093/molbev/msi237

Abstract

Detecting positive Darwinian selection at the DNA sequence level has been a subject of considerable interest. However, positive selection is difficult to detect because it often operates episodically on a few amino acid sites, and the signal may be masked by negative selection. Several ...read more

Mentioned in this Paper

In Silico
Likelihood Functions
Sense Codon
Codon Genus
Codon (Nucleotide Sequence)
Bayesian Prediction
Negative Selection
Positive Selection
Amino Acid [EPC]
Evolution, Molecular
2
741

Feeds With Similar Papers

Structure and Function of DNA

The double helix structure of DNA is important for its biological function. Discover the latest research on the Structure and Function of DNA here.

Related Papers

Molecular Biology and Evolution

Bayes empirical bayes inference of amino acid sites under positive selection

Molecular Biology and EvolutionFebruary 4, 2005
Ziheng YangRasmus Nielsen
Molecular Biology and Evolution

Codon-substitution models for detecting molecular adaptation at individual sites along specific lineages

Molecular Biology and EvolutionMay 29, 2002
Ziheng Yang, Rasmus Nielsen
Paper Details
References
  • References
  • Citations812
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations812
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