Evaluation of anterior segment parameters in patients with neurofibromatosis type 1

European Journal of Ophthalmology
Necati DuruEmin Özlü

Abstract

To evaluate anterior segment parameters in patients with neurofibromatosis type 1 (NF1) in comparison to healthy individuals. A total of 34 eyes from 17 patients with NF1 and 34 eyes from 17 age- and sex-matched healthy individuals were included in this study. Each participant underwent a comprehensive ophthalmic assessment including best-corrected visual acuity, slit-lamp biomicroscopy, stereoscopic fundus examination, and intraocular pressure. Central corneal thickness, corneal volume, corneal curvatures (K1 and K2), anterior chamber depth, anterior chamber volume, iridocorneal angle, and pupil size values were measured by Pentacam Scheimpflug camera. The mean anterior chamber depth, iridocorneal angle, and anterior chamber volume measurements revealed significantly lower values when compared with the control group (p<0.001, p<0.001, and p = 0.041, respectively). However, the mean pupil size was significantly larger when compared with the control group (p = 0.008). Central corneal thickness, corneal volume, K1, and K2 values were similar between the study and control groups (p = 0.875, p = 0.549, p = 0.066, and p = 0.166, respectively). Our results reveal that NF1 is associated with statistically significant alterations i...Continue Reading

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Citations

Jun 10, 2020·European Journal of Ophthalmology·Aldo VaggeCarlo E Traverso
Feb 6, 2020·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Zeynep Duru, Orhan Altunel
May 21, 2021·Indian Journal of Ophthalmology·Chrysoula FlorouIlias Georgalas

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