Evaluation of anti-pyretic and analgesic activity of Emblica officinalis Gaertn

Journal of Ethnopharmacology
James B PerianayagamA J M Christina

Abstract

The present study was designed to investigate the anti-pyretic and analgesic activity of ethanol (EEO) and aqueous (AEO) extracts of Emblica officinalis fruits in several experimental models. A single oral dose of EEO and AEO (500 mg/kg, i.p.) showed significant reduction in brewer's yeast induced hyperthermia in rats. EEO and AEO also elicited pronounced inhibitory effect on acetic acid-induced writhing response in mice in the analgesic test. Both, EEO and AEO did not show any significant analgesic activity in the tail-immersion test. These findings suggest that extracts of Emblica officinalis fruits possessed potent anti-pyretic and analgesic activity. Preliminary phytochemical screening of the extracts showed the presence of alkaloids, tannins, phenolic compounds, carbohydrates and amino acids, which may be responsible for anti-pyretic and analgesic activities.

References

Apr 1, 1990·Journal of Ethnopharmacology·S Palanichamy, S Nagarajan
Feb 1, 1968·British Journal of Pharmacology and Chemotherapy·H O CollierC Schneider
Jun 1, 1993·The Journal of Pharmacy and Pharmacology·M Z AsmawiH Vapaatalo
Jan 22, 1998·Planta medica·A Ihantola-VormistoE Moilanen
Sep 19, 1998·Journal of Ethnopharmacology·I AhmadF Mohammad
Jul 15, 1999·Phytotherapy Research : PTR·N N RegeS A Dahanukar
Apr 12, 2001·Journal of Ethnopharmacology·J K JoseR Kuttan
Aug 10, 2002·Journal of Ethnopharmacology·K SairamR K K Goel
May 1, 1963·Journal of Medicinal Chemistry·U M TEOTINOD DELLABELLA

❮ Previous
Next ❯

Citations

Jul 3, 2010·Inflammopharmacology·Arunachalam MuthuramanSumeet Kumar Singla
Apr 26, 2005·Journal of Ethnopharmacology·Letícia Veras Costa-LotufoManoel Odorico de Moraes
Oct 6, 2007·Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan·Mani Vasudevan, Milind Parle
May 29, 2010·Journal of Basic and Clinical Physiology and Pharmacology·Mani Krishnaveni, Sankaran Mirunalini
Feb 22, 2014·Journal of Natural Medicines·Bungorn Sripanidkulchai, Jintana Junlatat
Dec 11, 2014·Chinese Journal of Integrative Medicine·Bhakta Prasad Gaire, Lalita Subedi
Mar 6, 2013·Canadian Journal of Physiology and Pharmacology·Raja LathaPanchanadham Sachdanandam
Sep 4, 2010·International Journal of Ayurveda Research·Mradu GuptaA Mukherjee
Sep 24, 2013·Drug Development and Industrial Pharmacy·Rungsiri Chaiittianan, Bungorn Sripanidkulchai
Aug 9, 2012·Immunopharmacology and Immunotoxicology·Latha RajaSachdanandam Panchanatham
May 21, 2016·Evidence-based Complementary and Alternative Medicine : ECAM·Xin MaoLan-Zhen Zhang
Jul 17, 2010·Journal of Acupuncture and Meridian Studies·Mun Fei YamMohd Zaini Asmawi
Jun 21, 2016·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Bhavesh C VariyaSnehal S Patel
Dec 29, 2013·Journal of Agricultural and Food Chemistry·Baoru Yang, Pengzhan Liu
Oct 29, 2011·Toxicology and Industrial Health·Shreesh OjhaDharamvir Singh Arya
Mar 6, 2007·Phytotherapy Research : PTR·Rajendran MythilypriyaPanchanatham Sachdanandam
Jan 1, 2005·Pharmaceutical Biology·J B PerianayagamS G Vijayakumar

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anti-inflammatory Treatments

A drug or substance that reduces inflammation (redness, swelling, and pain) in the body. Anti-inflammatory agents block certain substances in the body that cause inflammation and swelling. Discover the latest research on anti-inflammatory treatments here