Evaluation of Antibiotic-Impregnated Mesh in Preventing the Recurrence of Capsular Contracture

Aesthetic Surgery Journal
Eric S RuffMalcolm J Rude

Abstract

Capsular contracture (CC) is the most frequently reported complication following breast augmentation. A growing body of evidence implicates subclinical (biofilm) infection around breast implants as an important cause of CC; however, effective prophylactic and treatment modalities remain controversial. This article aims to review a single surgeon's experience using an antibiotic-impregnated mesh as a prophylactic measure against biofilm formation and recurrent CC. This study retrospectively reviewed 5 consecutive patients presenting with CC (Baker grades III and IV) who were managed by capsulectomy with implant replacement and simultaneous insertion of an antibiotic-impregnated mesh. Patient demographics and major complications were recorded, including CC recurrence, reoperation, and infection. Complete correction of the contracture with no recurrence was achieved in all patients at a median followup of 25 months. This study demonstrates a novel technique using an antibiotic mesh to reduce bacterial access to breast implants at the time of insertion. Further investigation is warranted with more clinical cases in order to recommend this technique for the management of subclinical infection and CC.

References

Jul 1, 1981·Plastic and Reconstructive Surgery·B R BurkhardtJ J Tofield
Jan 12, 2001·Journal of Biomedical Materials Research·M KamelD Ibanez
Mar 26, 2003·Plastic and Reconstructive Surgery·Aniko PajkosYvonne E Cossart
Apr 4, 2006·Plastic and Reconstructive Surgery·William P AdamsSpencer A Brown
Jul 4, 2009·Pacing and Clinical Electrophysiology : PACE·Linda K HansenRabih Darouiche
Dec 3, 2009·Plastic and Reconstructive Surgery·Antonino AracoGianpiero Gravante
Apr 24, 2010·FEMS Immunology and Medical Microbiology·Iolanda Francolini, Gianfranco Donelli
Oct 15, 2010·Pacing and Clinical Electrophysiology : PACE·Heather L BloomUNKNOWN COoperative Multicenter study Monitoring a CIED ANtimicrobial Device Investigators
Mar 3, 2011·Plastic and Reconstructive Surgery·Mark A CodnerFoad Nahai
Jun 28, 2011·Plastic and Reconstructive Surgery·Luciano SilvestriPier Camillo Parodi
Sep 13, 2011·Aesthetic Surgery Journal·Sophie BartsichChristine Rohde
Dec 14, 2012·The Journal of Bone and Joint Surgery. American Volume·Andy T WeeJoaquin Sanchez-Sotelo
Dec 21, 2012·Pacing and Clinical Electrophysiology : PACE·Matthew J KolekChristopher R Ellis
Apr 13, 2013·Journal of Medical Microbiology·Michael P Ryan, Catherine C Adley
Sep 24, 2013·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M P Ryan, C C Adley
Dec 18, 2013·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Suneet MittalJonathan S Steinberg
Jun 23, 2015·Journal of Pain & Palliative Care Pharmacotherapy· U S Department Of Health And Human Services
Jul 30, 2015·Journal of Cardiovascular Electrophysiology·Matthew J KolekChristopher R Ellis
Feb 19, 2016·Plastic and Reconstructive Surgery·Honghua HuAnand K Deva
Feb 26, 2016·Plastic and Reconstructive Surgery·Dinah Wan, Rod J Rohrich
Jun 28, 2016·Applied and Environmental Microbiology·Camilla UrbaniakGregor Reid
Nov 1, 2017·Aesthetic Surgery Journal·Olga Zhadan, Hilton Becker

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Citations

Feb 13, 2019·Aesthetic Surgery Journal·Eric Swanson

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