Evaluation of antigen and antibody rapid detection tests for Trypanosoma evansi infection in camels in Kenya

Veterinary Parasitology
J M NgairaE N M Njagi

Abstract

The card agglutination test for Trypanosoma evansi (CATT/T. evansi) for the detection of antibodies, and Suratex for the detection of circulating antigens were compared in a cross-sectional study involving camels in eastern and central parts of Kenya. Of the 2227 camels screened, 2038 were owned by nomadic pastoralists in T. evansi endemic areas in eastern Kenya. A herd of 86 camels were from a ranch in Mugwoni. In Athi River area, 35 camels belonged to Kenya Trypanosomiasis Research Institute, and 68 were slaughter animals. Diagnostic sensitivity estimates were obtained by testing sera from 51 camels that had been found to be parasitologically positive by the haematocrit centrifugation technique, buffy-coat technique and mouse inoculation. Diagnostic specificity was estimated by testing sera from 35 camels known to be trypanosome-free. Positive and negative predictive values (NPVs) were calculated using a range of prevalence values. The sensitivity of CATT/T. evansi (68.6%) was higher than that of Suratex (58.8%), but not significantly. Both tests had equally high specificity (100%). The overall prevalence was 2.3% (51 out of 2227) by parasite detection, 32.2% (327 out of 1017) by CATT/T. evansi and 19.6% (188 out of 961) by S...Continue Reading

References

Feb 1, 1979·Tropical Animal Health and Production·A G LuckinsA R Gray
Jan 1, 1977·Transactions of the Royal Society of Tropical Medicine and Hygiene·M MurrayW I McIntyre
Jan 1, 1996·The British Veterinary Journal·W Olaho-MukaniJ O Ouma
May 10, 2000·Preventive Veterinary Medicine·M Greiner, I A Gardner
May 1, 1988·Parasitology Today·A G Luckins

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Citations

Sep 20, 2011·Parasitology Research·Nguyen Thu ThuyNoboru Inoue
Apr 5, 2005·Experimental Parasitology·J M NgairaJ J N Ngeranwa
Mar 17, 2004·Veterinary Parasitology·J M NgairaN K Olembo
Mar 1, 2015·Tropical Animal Health and Production·Abdirahman Abdikadir SalahAbdullahi Mohamed
Jan 25, 2018·Parasitology·Christine M KamidiGrace Murilla
Sep 8, 2017·PLoS Neglected Tropical Diseases·Christine M KamidiAdalgisa Caccone
May 1, 2009·Clinical and Vaccine Immunology : CVI·Thao TranPhilippe Büscher
Jun 10, 2019·Tropical Animal Health and Production·A A SalahA Sh Mohamed
Aug 9, 2020·Veterinary Sciences·Ellen Clare Hughes, Neil Euan Anderson

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