Evaluation of antimicrobial consumption in a Neonatology Unit: a team work to promote the rational use of antibiotics

Revista chilena de infectología : órgano oficial de la Sociedad Chilena de Infectología
Elisa JiménezPatricia Mena

Abstract

Antibiotics (ATB) are drugs widely used in hospitalized newborns. The indiscriminate use of ATBs promote the rise of resistant bacteria to the most commonly indicated antimicrobials. In addition, ATB prescription presents associations to morbidity, such as bronchopulmonary dysplasia, necrotizing enterocolitis, late sepsis and even death. All of the above leads to an increase in health care costs. To record and to evaluate trends of antibiotic use over time in hospitalized NB in the Neonatology Unit at Dr. Sótero del Río Hospital, in order to objectify the changes in the usual practice of the ATM indication. A secondary objective was to assess its impact on antimicrobial resistance. Cohort, observational, prospective unicenter study which included all hospitalized patients between January 2011 and December 2014. Birth weight, hospitalization days, ATB indication and days of ATB use were recorded for each patient. The use of ATB was quantified by means of different rates; days of indication of one or more ATBs for global consumption (RUA), total sum of days of use (TSUA) and for the most frequently used ATBs. Each calculated rate for 100 days hospitalized. In addition, the antimicrobial susceptibility of the most frequently isola...Continue Reading

Citations

Aug 9, 2020·International Journal of Environmental Research and Public Health·Asma Al-TurkaitShalini Ojha
Jun 30, 2021·Enfermedades infecciosas y microbiología clínica·Cristina Villanueva-BuenoUNKNOWN Paediatric Antimicrobial Defined Daily Dose Study Group (KiDDDs)

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