PMID: 7226591Jan 1, 1981Paper

Evaluation of aortic and mitral valve regurgitation by radionuclide ventriculography: comparison with the method of Sandler and Dodge

Clinical Cardiology
P KressW E Adam


The present investigation was undertaken to introduce a quantitative scintigraphic method for evaluation of regurgitation and to compare it with the generally accepted quantitative method of Sandler and Dodge (Sandler et al., 1963). Radionuclide ventriculography was carried out after injection of 20 mCi 99mtechnetium-labeled red blood cells. Time-activity curves were obtained from the left and right ventricular regions. The ratio (A) of end-diastolic-end-systolic count-rate differences for the left and right ventricles was calculated. The ratio (A) was compared with a hemodynamic ratio (Ah) determined after the method of Sandler and Dodge (1963) with the stroke volume of the left ventricle measured angiographically, and the stroke volume of the right ventricle measured by thermodilution. In 33 patients with aortic and mitral valve regurgitation we found a correlation of r = 0.75 between (A) and Ah). Due to a broad range of normal values of (A) the sensitivity of the scintigraphic method is low. The specificity seems to be high, however, since in 64 patients with all types of heart diseases there were no false positive results. Comparing the described scintigraphic method with other modern or generally accepted methods, the prin...Continue Reading


Jan 1, 1979·Catheterization and Cardiovascular Diagnosis·D Van NostrandH A Cohen
Jan 1, 1967·Circulation·D G GreeneI L Bunnell
Feb 1, 1972·The American Journal of Cardiology·W Ganz, H J Swan
Feb 1, 1973·The American Journal of Cardiology·G von BernuthE H Wood
Nov 1, 1974·The American Journal of Cardiology·D L KirchP P Steele
Jun 1, 1973·The American Journal of Cardiology·D HuntH T DODGE
Jul 1, 1969·The Annals of Thoracic Surgery·F J HildnerP Samet
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Sep 1, 1969·British Heart Journal·M HoneyV Thuraisingham
Dec 1, 1958·Circulation·C B CHAPMANF J BONTE
Apr 1, 1963·American Heart Journal·H SANDLERC E RACKLEY


Jan 1, 1985·European Journal of Nuclear Medicine·H NovackS F Horowitz
Aug 1, 1980·European Journal of Nuclear Medicine·A TarkowskaF Bitter
Jan 1, 1984·European Journal of Nuclear Medicine·J C LiehnJ L Valeyre
Sep 1, 1979·Cardiovascular Radiology·W E AdamH Geffers
Jan 1, 1984·Journal of the American College of Cardiology·M C GersonR J Adolph

Related Concepts

Aortic Valve Insufficiency
Mitral Valve Insufficiency
Stroke Volume
Technetium 99m

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