Evaluation of auditory brainstem potentials in children with acute Herpes simplex encephalitis

The International Journal of Neuroscience
Hüseyin CaksenOzlem Ozen

Abstract

In this study, auditory brainstem potentials (ABPs) were studied in children with Herpes simplex encephalitis (HSE) to determine the ABP abnormalities in HSE during childhood. We also wished to determine whether or not to use ABP in early diagnosis of HSE. The study includes 28 children; eight children with acute HSE, nine with nonspecific encephalitis, and 11 healthy age-matched control subjects. The diagnosis of HSE was confirmed by the demonstration of Herpes simplex virus type 1 in CSF by polymerase chain reaction. Recordings of ABPs were performed by using Nihon Kohden Neuropack 2 device. The study includes eight children (four females and four males) with acute HSE, nine children (five males and four females) with nonspecific encephalitis, and 11 healthy age-matched control subjects (six males and five females). Age ranges of the patients and controls were between six months and 12 years. There was not statistically significant difference between the groups for age and gender (p > .05). There were significant differences in the mean latencies of the wave IV on the right ear and in the mean interpeak latencies (IPLs) of the waves III-V on the right and left ears between the nonspecific encephalitis group and the control gr...Continue Reading

References

Feb 1, 1996·The International Journal of Neuroscience·G SchwarzR Reimann
Jul 30, 1999·Journal of the Neurological Sciences·J Kalita, U K Misra
Apr 19, 2003·Acta Oto-laryngologica·Kimitaka KagaMitsuko Shindo
Feb 3, 2005·Seminars in Pediatric Infectious Diseases·Richard J Whitley, David W Kimberlin

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