Evaluation of automatic measurement of the intracranial volume based on quantitative MR imaging.

AJNR. American Journal of Neuroradiology
K AmbarkiA Eklund

Abstract

Brain size is commonly described in relation to ICV, whereby accurate assessment of this quantity is fundamental. Recently, an optimized MR sequence (QRAPMASTER) was developed for simultaneous quantification of T1, T2, and proton density. ICV can be measured automatically within minutes from QRAPMASTER outputs and a dedicated software, SyMRI. Automatic estimations of ICV were evaluated against the manual segmentation. In 19 healthy subjects, manual segmentation of ICV was performed by 2 neuroradiologists (Obs1, Obs2) by using QBrain software and conventional T2-weighted images. The automatic segmentation from the QRAPMASTER output was performed by using SyMRI. Manual corrections of the automatic segmentation were performed (corrected-automatic) by Obs1 and Obs2, who were blinded from each other. Finally, the repeatability of the automatic method was evaluated in 6 additional healthy subjects, each having 6 repeated QRAPMASTER scans. The time required to measure ICV was recorded. No significant difference was found between reference and automatic (and corrected-automatic) ICV (P > .25). The mean difference between the reference and automatic measurement was -4.84 ± 19.57 mL (or 0.31 ± 1.35%). Mean differences between the referen...Continue Reading

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Citations

Feb 28, 2013·International Journal of Computer Assisted Radiology and Surgery·Antti G RitvanenMervi M Paulasto-Kröckel
Sep 15, 2012·AJNR. American Journal of Neuroradiology·M VågbergA Svenningsson
Mar 31, 2015·Neuroinformatics·Saman SargolzaeiMalek Adjouadi
Dec 26, 2015·AJNR. American Journal of Neuroradiology·J VirhammarE-M Larsson
Jan 23, 2016·AJNR. American Journal of Neuroradiology·T GranbergM Kristoffersen-Wiberg
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Aug 11, 2019·Journal of Neuroradiology. Journal De Neuroradiologie·Maxence SerruBaptiste Morel
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