Evaluation of bone marrow aspirates from multiple sites for staging of canine lymphoma and mast cell tumours

Veterinary and Comparative Oncology
O A AubryA N Smith

Abstract

This prospective study evaluated the utility of bone marrow aspirates (BMAs) obtained from multiple sites for staging of canine lymphoma (LSA) and mast cell tumours (MCTs). Forty dogs (LSA, n = 24; MCTs, n = 16) were enrolled, but only 33 (82.5%) had diagnostic bone marrow (BM) aspirates obtained from two sites for inclusion in the study. Nineteen dogs with LSA were included, and 6 (31.6%) had BM involvement. Neoplastic lymphocytes were present in BM from both sites in all of these dogs. Fourteen dogs with MCTs were included, and 3 (21.4%) had BM involvement. Neoplastic mast cells were present at both sites in two dogs and at only one site in the third. These results indicate that BMAs from multiple sites may not be needed for accurate staging of canine LSA patients, but more studies evaluating the pattern of BM infiltration in dogs with high-grade MCTs are warranted.

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Citations

Mar 10, 2016·The Veterinary Quarterly·M Zandvliet
Aug 21, 2014·Veterinary Clinical Pathology·Emily C GraffMinerva Brauss
Nov 20, 2019·The Journal of Small Animal Practice·J M Dobson

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