PMID: 6980356Aug 1, 1982Paper

Evaluation of bone mass and growth in young diabetics

Metabolism: Clinical and Experimental
P S WiskeC C Johnston

Abstract

To determine the relationships among bone mass, bone growth and serum glucose control in young, insulin-dependent diabetics, we performed photon absorptiometry and radiogrammetry on a clinically well-characterized group of 78 diabetics (mean age 15.2 yr, mean duration of diabetes 6.7 yr). Total and ionized calcium (TCa, ICa), magnesium (Mg), immunoreactive parathyroid hormone (iPTH) and phosphorus (P) were measured in fasting serum. Bone age was calculated from hand x-rays; and bone measurements, heights, and weights were standardized against normal groups of corresponding age, sex, and race. Mean deviation of bone mass measurement score was 1.24 SD below the normal mean (p less than .001); mean cortical area score was .22 SD and percent cortical area .25 SD below the normal means (both p less than .05). Radical width and metacarpal width for the diabetics were not less than normal. Mean percentiles for height and weight were 52.3 and 57.1 respectively, the latter significantly elevated (p less than .02). Bone mass and cortical area were inversely related to duration of disease (r = -.228, p less than .05; r = -.216, p less than .05). They were not correlated with serum parameters of mineral metabolism or of glucose control. Bo...Continue Reading

References

Oct 1, 1978·Clinical Endocrinology·P RaskinC Y Pak
Nov 1, 1979·Diabetologia·P McNairI Transbøl
Mar 1, 1979·Acta Endocrinologica·P McNairI Transbøl
Jun 21, 1979·The New England Journal of Medicine·P S WiskeC C Johnston
Sep 1, 1979·The Journal of Clinical Endocrinology and Metabolism·H HeathS B Arnaud
Jun 1, 1978·Clinica Chimica Acta; International Journal of Clinical Chemistry·S C ConceicaoD N Kerr
Jul 1, 1978·Acta paediatrica Scandinavica·H Draminsky PetersenE Nielsen
Oct 1, 1977·The Journal of Clinical Endocrinology and Metabolism·J V SantiagoV V Weldon
May 11, 1975·Metabolism: Clinical and Experimental·E ManzkeW B Nelp
Jan 29, 1976·The New England Journal of Medicine·M E LevinL V Avioli
Nov 17, 1973·Lancet·R B Tattersall, D A Pyke
Aug 1, 1972·Archives of Disease in Childhood·N EvansJ Lister
Mar 1, 1974·The Journal of Clinical Endocrinology and Metabolism·L R Chase, E Slatopolsky
Aug 1, 1974·Archives of Disease in Childhood·N M Drayer
Apr 17, 1969·The New England Journal of Medicine·L Zacharias, R J Wurtman
Jul 1, 1972·Diabetologia·J A Birkbeck
Aug 18, 1972·Science·C S AnastT W Burns
Oct 15, 1971·American Journal of Obstetrics and Gynecology·J WeirE G Jones
Feb 18, 1971·The New England Journal of Medicine·L A TrivelliH T Lai
Jan 1, 1971·The Journal of Clinical Investigation·C D ArnaudT Littledike
Jan 1, 1971·Investigative Radiology·R B Mazess
Jan 1, 1967·Acta paediatrica Scandinavica·G Sterky
Oct 1, 1968·Annals of Internal Medicine·C E Jackson, D W Meier
Dec 1, 1968·Metabolism: Clinical and Experimental·C C JohnstonW P Deiss
May 1, 1980·The Journal of Clinical Endocrinology and Metabolism·J M GertnerM Genel
Feb 1, 1981·European Journal of Clinical Investigation·P McNairI Transbøl
Jan 1, 1981·Calcified Tissue International·R M ShoreG J Bargman

❮ Previous
Next ❯

Citations

Dec 1, 1989·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·K K PunP W Ho
Oct 1, 1989·Acta diabetologica latina·C GazzarriniB De Bernard
Jan 1, 1988·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·T A EinhornM M Beyer
Apr 1, 1994·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·S EpsteinW S Jee
May 1, 1993·Diabetic Medicine : a Journal of the British Diabetic Association·N C ThalassinosD Philokiprou
Oct 1, 1987·Acta diabetologica latina·G IsaiaG M Molinatti
Apr 1, 1986·European Journal of Pediatrics·K Kruse, U Kracht
Jul 14, 1983·The New England Journal of Medicine·L G Raisz, B E Kream
Sep 1, 1991·Calcified Tissue International·R Bouillon
Jul 9, 1999·Clinical Endocrinology·J J Hoorweg-NijmanH A Delemarre-van de Waal
Mar 1, 1993·Diabetic Medicine : a Journal of the British Diabetic Association·S J GallacherA C MacCuish
Apr 1, 1995·Diabetes/metabolism Reviews·Y Seino, H Ishida
Mar 1, 1993·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·J C HouR J Barnard
Dec 16, 2000·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·T VidemanH Manninen
Jan 1, 1994·Critical Reviews in Clinical Laboratory Sciences·V O Van Hoof, M E De Broe
Oct 5, 2001·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·P J López-IbarraM A Diosdado
Jul 1, 1997·Isotopes in Environmental and Health Studies·E J Freyse, S Knospe
Sep 16, 2006·Endocrinology·Regina IrwinLaura R McCabe
Apr 19, 2006·Journal of Cellular Biochemistry·Sergiu Botolin, Laura R McCabe
Sep 15, 2006·Journal of Cellular Physiology·Sergiu Botolin, Laura R McCabe
Oct 11, 2019·Pediatric Diabetes·Olga Slavcheva-ProdanovaMargarita Archinkova
Nov 5, 1998·Aging : Clinical and Experimental Research·C GennariR Nuti
Jul 1, 1988·Diabetic Medicine : a Journal of the British Diabetic Association·P L Selby
Aug 1, 1994·Journal of Internal Medicine·T M MelchiorC Torp-Pedersen
Nov 1, 1985·Diabetic Medicine : a Journal of the British Diabetic Association·T F CundyP J Watkins
Jan 1, 1987·The American Journal of Physiology·N BankH S Aynedjian
Feb 13, 2001·Bone·E BalintS M Sprague
Jan 1, 1988·Bone·A GiaccaG Pozza
Feb 1, 1990·Bone and Mineral·M E LocattoR C Puche
Aug 1, 1989·Seminars in Arthritis and Rheumatism·D A Watrous, B S Andrews

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diabetes & Tolerance

Patients with type I diabetes lack insulin-producing beta cells due to the loss of immunological tolerance and autoimmune disease. Discover the latest research on targeting tolerance to prevent diabetes.