Evaluation of C-reactive protein/albumin ratio and its relationship with survival in dogs with acute pancreatitis.

New Zealand Veterinary Journal
E GoriV Marchetti

Abstract

Aims: To evaluate the association between the C-reactive protein (CRP)/albumin (ALB) ratio and survival in dogs with acute pancreatitis and its use as a prognostic marker for survival. Methods: Medical records of a veterinary referral hospital in Italy were retrospectively searched for dogs that were admitted with acute pancreatitis between January 2015 and April 2019, in which the concentrations of CRP and ALB in serum were measured at admission. The CRP/ALB ratio was calculated and the time between admission and discharge or death was recorded. Mortality rates overall and for dogs that died within 2 days of admission were calculated. A univariable Cox proportional hazard model was used to assess the relationship between survival time and CRP/ALB ratio. Results: Seventy-one dogs were included in the study. Of these, 19 died within 2 days of presentation; an early mortality rate of 26.8%, while 27 died before discharge for an overall mortality rated of 38%. Dogs with higher CRP/ALB ratio had a significantly greater mortality rate than dogs with lower CRP/ALB ratio: for every 1-unit increase in CRP/ALB ratio, the hazard of death over the study period increased by 130% (hazard ratio = 2.34; 95% CI = 1.53-3.58; p < 0.001). The opt...Continue Reading

References

Sep 18, 2008·Journal of the American Veterinary Medical Association·Caroline S MansfieldIan D Robertson
Mar 1, 2011·Acta Veterinaria Hungarica·Kinga PápaKároly Vörös
Jan 15, 2015·The Journal of Small Animal Practice·P G Xenoulis
Sep 27, 2016·The Journal of Veterinary Medical Science·Toru SatoHajime Tsujimoto
Aug 22, 2017·Hepatobiliary & Pancreatic Diseases International : HBPD INT·Mustafa KaplanErtugrul Kayacetin
Oct 28, 2017·Australian Veterinary Journal·V MarchettiA Pierini
Aug 30, 2018·Journal of Neurogastroenterology and Motility·Seung Wook HongJoo Sung Kim
Oct 10, 2018·Journal of Clinical Medicine·Ji Eun ParkAh Young Leem
Dec 21, 2018·Journal of Palliative Medicine·Tomoyoshi MiyamotoAtsufumi Kawabata
Mar 2, 2019·The Veterinary Journal·E GoriV Marchetti

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Citations

Nov 10, 2021·Journal of Veterinary Internal Medicine·Harry CridgeJörg M Steiner

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