Evaluation of cardiovascular disease risk in women with surgically induced menopause

Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology
Nagihan SariMuhammet Fevzi Polat

Abstract

This study evaluates cardiovascular disease (CVD) risk among women undergoing natural menopause or surgically induced menopause through the measurement of serum growth differentiation factor-15 (GDF-15), B-type natriuretic peptide (BNP), ischemia modified albumin (IMA), total cholesterol, LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), triglyceride, fibrinogen, and C-reactive protein (CRP). The study included women with surgically induced menopause (n = 50) and women undergoing natural menopause (n = 50). The two study groups were matched according to age, body mass index, menopause duration. GDF-15, BNP, IMA, total cholesterol, LDL-C, HDL-C, triglyceride, fibrinogen, and CRP were measured. There was no significant difference in GDF-15, BNP, IMA, total cholesterol, LDL-C, HDL-C, triglyceride, fibrinogen, and CRP results between the two groups. We conclude that there is no increase in CVD risk among women aged 40-50 with surgically induced menopause relative to matched control subjects undergoing normal age-related menopause.

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Citations

Mar 13, 2021·Biomarkers in Medicine·Mehmet F KıncıAhmet A Sivaslıoğlu
Nov 25, 2020·Journal of cardiology·Majke H D van BommelAngela H E M Maas

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