Abstract
This study evaluates cardiovascular disease (CVD) risk among women undergoing natural menopause or surgically induced menopause through the measurement of serum growth differentiation factor-15 (GDF-15), B-type natriuretic peptide (BNP), ischemia modified albumin (IMA), total cholesterol, LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), triglyceride, fibrinogen, and C-reactive protein (CRP). The study included women with surgically induced menopause (n = 50) and women undergoing natural menopause (n = 50). The two study groups were matched according to age, body mass index, menopause duration. GDF-15, BNP, IMA, total cholesterol, LDL-C, HDL-C, triglyceride, fibrinogen, and CRP were measured. There was no significant difference in GDF-15, BNP, IMA, total cholesterol, LDL-C, HDL-C, triglyceride, fibrinogen, and CRP results between the two groups. We conclude that there is no increase in CVD risk among women aged 40-50 with surgically induced menopause relative to matched control subjects undergoing normal age-related menopause.
References
Apr 30, 1987·The New England Journal of Medicine·G A ColditzC H Hennekens
Jan 1, 1993·American Journal of Public Health·K KjerulffG Guzinski
Jun 1, 1997·Journal of Women's Health·K M BrettJ H Madans
Feb 3, 2000·Journal of Epidemiology and Community Health·E BrunnerM G Marmot
Apr 14, 2005·The Journal of Clinical Endocrinology and Metabolism·S L DavisonS R Davis
Jun 16, 2005·Maturitas·E LøkkegaardA T Pedersen
Apr 29, 2006·Menopause : the Journal of the North American Menopause Society·Femke AtsmaYvonne T van der Schouw
Jan 1, 2008·Obstetrics and Gynecology·UNKNOWN ACOG
Feb 20, 2010·Obstetrics and Gynecology·Vanessa L JacobyAlison Jacoby
Apr 27, 2011·Archives of Internal Medicine·Vanessa L JacobyMarcia L Stefanick
Aug 16, 2011·Maturitas·Konstantinos KazanisAmalia Dionyssiou-Asteriou
May 3, 2013·Obstetrics and Gynecology·William H ParkerJoann E Manson
May 21, 2013·Journal of the American College of Cardiology·Karen A MatthewsRebecca C Thurston
Jul 16, 2014·Clinical Laboratory·Lie Ying FanZhong Min Liu
Aug 27, 2014·International Journal of Cardiology·Chaitanya MadamanchiMarschall S Runge
Aug 30, 2014·PloS One·Abdelkader KahliCatherine Vergely
Oct 3, 2014·Circulation·Vanessa XanthakisRamachandran S Vasan
Citations
Apr 18, 2019·Journal of Cardiovascular Imaging·Murat AkcayOzcan Yılmaz
Mar 13, 2021·Biomarkers in Medicine·Mehmet F KıncıAhmet A Sivaslıoğlu
Nov 25, 2020·Journal of cardiology·Majke H D van BommelAngela H E M Maas