Evaluation of carotid artery outward remodeling by T1-weighted magnetic resonance imaging in carotid endarterectomy and stenting

Journal of Vascular Surgery
Daisuke MaruyamaKoji Iihara

Abstract

We evaluated carotid artery outward remodeling and plaque relative signal intensity (rSI) using T1-weighted magnetic resonance imaging (T1-MRI) to investigate their clinical significance in carotid revascularization. From 86 patients undergoing carotid endarterectomy (CEA) or carotid artery stenting (CAS), 88 lesions (51 lesions treated with CEA and 37 lesions treated with CAS) were analyzed retrospectively. We evaluated the preoperative carotid artery remodeling index (CRI), determined by a ratio of the external cross-sectional vessel area at maximum stenosis and the reference cross-sectional vessel area at the distal portion of the internal carotid artery, and the plaque rSI, which is quantified as the ratio between the signal intensities of plaque and adjacent muscle using T1-MRI. We divided carotid lesions into four groups using the median values of CRI and rSI: L/L (CRI < 1.8, rSI < 2.5), H/L (CRI ≥ 1.8, rSI < 2.5), L/H (CRI < 1.8, rSI ≥ 2.5), and H/H (CRI ≥ 1.8, rSI ≥ 2.5). The primary end point was detection of acute ipsilateral ischemia on diffusion-weighted imaging (DWI) within 72 hours of treatment. Mean CRI and rSI were significantly higher in lesions treated with CEA than in those treated with CAS. Postoperative DWI...Continue Reading

References

Aug 15, 1991·The New England Journal of Medicine·UNKNOWN North American Symptomatic Carotid Endarterectomy Trial CollaboratorsM Eliasziw
May 28, 1987·The New England Journal of Medicine·S GlagovG J Kolettis
Feb 28, 2002·Circulation·Amanda M VarnavaMichael J Davies
Mar 24, 2007·Stroke; a Journal of Cerebral Circulation·Nishath AltafDorothee P Auer
May 26, 2011·Journal of Vascular Surgery·Carlos H TimaranFred Littooy
Jan 1, 2011·Cerebrovascular Diseases Extra·Toshiyasu MiuraKosei Ojika
Nov 22, 2012·Stroke; a Journal of Cerebral Circulation·Hiroshi TanemuraWaro Taki
Mar 4, 2014·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Kenji FukudaHatsue Ishibashi-Ueda

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carotid Artery Diseases

Carotid artery disease is a group of pathological conditions of the carotid artery. Discover the latest research on carotid artery disease here.

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.