PMID: 44907Jan 1, 1979

Evaluation of cefaclor and amoxycillin in the treatment of acute otitis media

Postgraduate Medical Journal
J A JacobsonJ M Matsen

Abstract

Twenty-eight patients with acute otitis media were treated in a random double blind manner with either amoxycillin or cefaclor. The predominant organisms isolated were H. influenzae and S. pneumoniae. All patients responded satisfactorily except one, treated with cefaclor, whose compliance with the regimen was very doubtful. One instance of mild elevation of SGOT and one case of mild erythematous rash occurred in each treatment group. In this limited study, cefaclor appeared comparable to amoxycillin in the treatment of acute otitis media.

Related Concepts

Haemophilus influenzae
Wymox
Acute Disease
Lilly 99638
Clinical Trials
Cephalexin, Monosodium Salt, (6R-(6alpha,7beta))-Isomer
Otitis Media
Streptococcus pneumoniae
Double-Blind Method

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